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Carbonic Anhydrase II Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of human carbonic anhydrase 2 assessed as Ki by stopped-flow carbon dioxide hydration assay
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human CA2 by UV spectrophotometric analysis
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Potency index, ratio of acetazolamide IC50 to test compound IC50 for inhibition of human CA2
Assay data:8 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human CA2
Assay data:54 Active, 54 Activity ≤ 1 µM, 54 Tested
Inhibition of human recombinant CA2
Assay data:8 Active, 7 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay
Binding affinity to human CA2 by phenol red dye based stopped flow CO2 hydration assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 17 Tested
Binding affinity to human CA2 assessed as inhibition constant
Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human cytosolic carbonic anhydrase 2 using 4-nitrophenyl acetate as substrate assessed as inhibition constant by spectrophotometric analysis
Inhibition of human carbonic anhydrase 2 assessed as inhibition constant
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Binding affinity to human carbonic anhydrase 2 assessed as Gibbs free energy change
Assay data:10 Tested
Inhibition of human carbonic anhydrase 2 assessed as inhibition constant by stopped-flow CO2 hydration assay
Assay data:10 Active, 1 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of recombinant human carbonic anhydrase 2 preincubated for 10 mins and measured by phenol red based stopped-flow CO2 hydration assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 28 Tested
Binding affinity to human CA2 assessed as inhibition constant using p-nitrophenylacetate as substrate by spectrophotometry
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of recombinant human CA 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assay
Assay data:18 Active, 14 Activity ≤ 1 µM, 18 Tested
Inhibition of His-tagged recombinant human Carbonic anhydrase 2 expressed in Escherichia coli using 4-nitrophenyl acetate as substrate at 5 uM incubated for 30 mins followed by substrate addition fluorescence based analysis
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