BioAssay by Target (List) for Gene (Select 779) - PubChem BioAssay - NCBI

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Select item 19144471.

Selectivity interaction (Enzyme panel (Eurofins-Cerep)) EUB0000263b CACNA1S

Source:: ChEMBL

Protein Target:: Voltage-dependent L-type calcium channel subunit alpha-1S

Assay data:1 Tested

AID:: 1914447

Summary Related BioAssays by Target

Select item 19144462.

Selectivity interaction (CEREP panel (Eurofins)) EUB0000263b CACNA1S

Source:: ChEMBL

Protein Target:: Voltage-dependent L-type calcium channel subunit alpha-1S

Assay data:1 Tested

AID:: 1914446

Summary Related BioAssays by Target

Select item 18743663.

Inhibition of L-type calcium channel phenylalkylamine site (unknown origin) at 10 uM relative to control

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:3 Tested

AID:: 1874366

Summary PubMed Citation Related BioAssays by Target

Select item 18265734.

Inhibition of calcium channel, Type L (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1826573

Summary PubMed Citation Related BioAssays by Target

Select item 17913675.

Ca2+ channel (L, verapamil site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1791367

Summary Related BioAssays by Target

Select item 17913666.

Ca2+ channel (L, diltiazem site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1791366

Summary Related BioAssays by Target

Select item 17913657.

Ca2+ channel (L, DHP site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1791365

Summary Related BioAssays by Target

Select item 17913118.

Ca2+ channel (L, verapamil site) (phenylalkylamines) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1791311

Summary Related BioAssays by Target

Select item 17913109.

Ca2+ channel (L, diltiazem site) (benzothiazepines) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1791310

Summary Related BioAssays by Target

Select item 179130910.

Ca2+ channel (L, DHP site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1791309

Summary Related BioAssays by Target

Select item 178875711.

Ca2+ channel CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788757

Summary Related BioAssays by Target

Select item 178866812.

Ca2+ channel (L, dihydropyridine site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788668

Summary Related BioAssays by Target

Select item 178865213.

Ca2+ channel (L, diltiazem site) (benzothiazepines) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788652

Summary Related BioAssays by Target

Select item 178846414.

Ca2+ channel (L, dihydropyridine site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788464

Summary Related BioAssays by Target

Select item 178844715.

Ca2+ channel (L, diltiazem site) (benzothiazepines) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788447

Summary Related BioAssays by Target

Select item 178838916.

Ca2+ channel (L, verapamil site) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788389

Summary Related BioAssays by Target

Select item 178831317.

Ca2+ channel (L verapamil site) Ligand binding assay

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788313

Summary Related BioAssays by Target

Select item 178823618.

Ca2+ channel CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1788236

Summary Related BioAssays by Target

Select item 178531219.

Inhibition of L type calcium channel (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:2 Tested

AID:: 1785312

Summary PubMed Citation Related BioAssays by Target

Select item 175167120.

Inhibition of calcium channel, Type L (unknown origin) at 0.1 to 1 uM

Source:: ChEMBL

Protein Targets:: Voltage-dependent L-type calcium channel subunit alpha-1C; ...
Total:: 4

Assay data:1 Tested

AID:: 1751671

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (14)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (73)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (4)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (35)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (111)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (13)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (223)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (11)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (194)
BioAssays extracted from the literature
NIH MLP (14)
BioAssays deposited by the NIH Molecular Libraries Program
Other (28)
BioAssays deposited by other experimentalists

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