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Inhibition of tubulin polymerization (unknown origin) by fluorescence assay relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of tubulin polymerization (unknown origin) incubated for 15 mins followed by GTP addition and measured for 20 mins by spectrophotometry
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Induction of microtubule stabilization in human HeLa cells assessed as effect on cellular cytoskeletal network of tubulin at 5 to 10 uM incubated for 4 hrs by Alexa Fluor 488 staining based confocal microscopic analysis
Assay data:2 Active, 2 Tested
Induction of microtubule stabilization (unknown origin) at 1 to 5 uM
Induction of microtubule stabilization (unknown origin) at 0.2 to 5 uM
Induction of microtubule destabilization (unknown origin) at 5 uM
Assay data:1 Tested
Induction of microtubule stabilization (unknown origin) at 5 uM
Inhibition of tubulin polymerization in human HCT-116 cells
Inhibition of tubulin polymerization in human HCT-116 cells at 0.55 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 6.50 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 3.25 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 1.62 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization in human HCT-116 cells at 3 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization (unknown origin) at 3 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of tubulin polymerization in human HCT-15 cells by immunofluorescence analysis
Inhibition of tubulin polymerization (unknown origin) at 1.73 to 6.92 uM measured after 1 hr relative to control
Inhibition of tubulin polymerization (unknown origin) at 1.73 to 6.92 uM measured after 1 hr
Inhibition of tubulin polymerization (unknown origin) assessed as decrease in fluorescence intensity at 2 uM
Disruption of microtubule organization in human HepG2 cells assessed as cell shrinkage at 50 to 200 nM by immunofluorescence staining based laser confocal microscopic analysis
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