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Inhibition of TAMRA-FP binding to human ABHD16A expressed in HEK293 cells at 20 to 200 uM preincubated for 1 hr followed by TAMRA-FP addition measured after 1 hr by fluorescence based ABPP analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Ratio of IC50 for reversible inhibition of human ABHD16A expressed in HEK293 cells to IC50 for inhibition of human ABHD16A expressed in HEK293 cells
Assay data:3 Tested
Inhibition of human ABHD16A expressed in HEK293 cells assessed as residual activity at 100 uM preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control
Assay data:2 Tested
Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG substrate addition and measured at 30 mins time interval for 120 mins by fluorometric assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins by fluorometric assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of human ABHD16A expressed in HEK293 cells assessed as residual activity at 10 uM preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control
Assay data:20 Tested
Potency index, ratio of tetrahydrolipstatin IC50 to compound IC50 for inhibition of ABHD16A (unknown origin)
Inhibition of ABHD16A (unknown origin)
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of BAT5 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of recombinant BAT5 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
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