BioAssay by Target (List) for Gene (Select 79858) - PubChem BioAssay - NCBI

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Select item 19488511.

Inhibition of NEK11 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:40 Tested

AID:: 1948851

Summary PubMed Citation Related BioAssays by Target

Select item 19488402.

Inhibition of NEK11 (unknown origin) at 10 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:10 Tested

AID:: 1948840

Summary PubMed Citation Related BioAssays by Target

Select item 19488303.

Inhibition of NEK11 (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested

AID:: 1948830

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19015034.

Inhibition of human full length recombinant NEK11 assessed as residual activity at 1 uM using myelin basic protein as substrate incubated for 40 mins in presence of [gamma 33P]-ATP by radiometric scintillation counting assay relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1901503

Summary PubMed Citation Related BioAssays by Target

Select item 18356225.

NEK11 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1835622

Summary Related BioAssays by Target

Select item 18350796.

NEK11(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1835079

Summary Related BioAssays by Target

Select item 18342417.

Inhibition of NEK11 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1834241

Summary PubMed Citation Related BioAssays by Target

Select item 17942238.

KinomeScan assay: inhibition of NEK11

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:108 Tested

AID:: 1794223

Summary Related BioAssays by Target

Select item 17937519.

Nek11(NE11LGRI) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793751

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179346310.

Nek11(NE11LGRI) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793463

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179316911.

Nek11(NE11LGRI) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793169

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179277912.

NEK11(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1792779

Summary Related BioAssays by Target

Select item 179238813.

NEK11 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1792388

Summary Related BioAssays by Target

Select item 179149314.

NEK Invitrogen kinase activity assay

Source:: ChEMBL

Protein Targets:: Serine/threonine-protein kinase Nek1; ...
Total:: 11

Assay data:1 Tested

AID:: 1791493

Summary Related BioAssays by Target

Select item 178938315.

NEK11(h) Eurofins Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1789383

Summary Related BioAssays by Target

Select item 178906516.

NEK11 (h) Millipore kinase activity assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1789065

Summary Related BioAssays by Target

Select item 178742517.

NEK11(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1787425

Summary Related BioAssays by Target

Select item 178690518.

NIMA -related kinase 11 Millipore kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:1 Tested

AID:: 1786905

Summary Related BioAssays by Target

Select item 174949219.

Inhibition of NEK11 (unknown origin) assessed as residual activity measured at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:3 Tested

AID:: 1749492

Summary Related BioAssays by Target

Select item 174918820.

Inhibition of NEK11 (unknown origin) assessed as residual activity at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase Nek11

Assay data:2 Tested

AID:: 1749188

Summary Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (6)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (7)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (10)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (82)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (63)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (62)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 79858) (127)
PubChem BioAssay
Homo sapiens NIMA related kinase 11 (NEK11), transcript variant 11, mRNA
Homo sapiens NIMA related kinase 11 (NEK11), transcript variant 11, mRNA
gi|1675158015|ref|NM_001353024.2|

Nucleotide

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