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Calcitonin Eurofins-Panlabs radioligand binding assay
Assay data:3 Tested
SummaryRelated BioAssays by Target
PRESTO-Tango GPCRome screening (CALCRb)
Assay data:1 Tested
Antagonist activity at human adrenomedullin-1 receptor
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at human amylin-1 receptor
Displacement of [125I]-labeled human calcitonin from human calcitonin receptor expressed in BHK tkts13 whole cells incubated for 60 mins by scintillation proximity assay
Assay data:91 Active, 50 Activity ≤ 1 nM, 91 Activity ≤ 1 µM, 91 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Displacement of [125I]-labeled rat amylin from human amylin receptor expressed in BHK tkts13 whole cells co-expressing RAMP3 incubated for 60 mins by scintillation proximity assay
Assay data:91 Active, 48 Activity ≤ 1 nM, 91 Activity ≤ 1 µM, 91 Tested
Displacement of [125I]-labeled rat calcitonin from human calcitonin receptor expressed in BHK tkts13 cell membranes incubated for 1 hr by scintillation proximity assay
Assay data:35 Active, 35 Activity ≤ 1 nM, 35 Activity ≤ 1 µM, 39 Tested
Displacement of [125I]-labeled human calcitonin from human calcitonin receptor expressed in BHK tkts13 cell membranes incubated for 1 hr by scintillation proximity assay
Assay data:39 Active, 39 Activity ≤ 1 nM, 39 Activity ≤ 1 µM, 39 Tested
Displacement of [125I]-labeled rat amylin from human amylin receptor expressed in BHK570 cell membranes co-expressing RAMP3 incubated for 120 mins by scintillation proximity assay
Agonist activity at human calcitonin receptor expressed in BHK570 cells assessed as increase in intracellular cAMP concentration incubated for 3 hrs in presence of 10% FBS by CRE luciferase reporter gene assay
Assay data:96 Active, 96 Activity ≤ 1 nM, 96 Activity ≤ 1 µM, 96 Tested
Agonist activity at human amylin receptor expressed in BHK570 cells co-expressing RAMP3 assessed as increase in intracellular cAMP concentration incubated for 3 hrs in presence of 10% FBS by CRE luciferase reporter gene assay
Agonist activity at human calcitonin receptor expressed in BHK570 cells assessed as increase in intracellular cAMP concentration incubated for 3 hrs in absence of albumin by CRE luciferase reporter gene assay
Assay data:141 Active, 141 Activity ≤ 1 nM, 141 Activity ≤ 1 µM, 143 Tested
Agonist activity at human amylin receptor expressed in BHK570 cells co-expressing RAMP3 assessed as increase in intracellular cAMP concentration incubated for 3 hrs in absence of albumin by CRE luciferase reporter gene assay
Assay data:141 Active, 140 Activity ≤ 1 nM, 141 Activity ≤ 1 µM, 143 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Human CT receptor (Calcitonin receptors)
Assay data:11 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human calcitonin receptor at 10 uM relative to control
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
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