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Evaluation of DGKdelta Inhibitory Effect from US Patent US20240043403: "HETEROARYL CARBOXAMIDE COMPOUND"
Assay data:120 Active, 2 Activity ≤ 1 nM, 119 Activity ≤ 1 µM, 120 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of DGKdelta (unknown origin) expressed in human 293T cells at 100 uM using DAG as substrate measured after 5 mins in presence of [gamma-32P]ATP by TLC analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Primary screen of kinases in signalling pathway between Protease activated receptor 2 (PAR2) and the ion channels Transient receptor potential vanilloid-4 (TRPV4) in HEK293 cells
Assay data:91 Active, 714 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW620)
Assay data:15 Active, 794 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC5)
Assay data:11 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCT15)
Assay data:18 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (CAR1)
Assay data:9 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT55)
Assay data:20 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (RCM1)
Assay data:13 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT29)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC1)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (LS513)
Assay data:16 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (NCIH630)
Assay data:17 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCC56)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW48)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT115)
Assay data:14 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (DIFI)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (COLO678)
Assay data:22 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNU407)
Assay data:12 Active, 794 Tested
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