BioAssay by Target (List) for Gene (Select 8576) - PubChem BioAssay - NCBI

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Select item 19142671.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000724a STK16

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914267

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19142662.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000724a STK16

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1914266

Summary Related BioAssays by Target

Select item 19140773.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000138c STK16

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1914077

Summary Related BioAssays by Target

Select item 19139484.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000702a STK16

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1913948

Summary Related BioAssays by Target

Select item 19138165.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000691a STK16

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1913816

Summary Related BioAssays by Target

Select item 19025936.

Inhibition of MPSK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1902593

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18890177.

Inhibition of STK16 (unknown origin) at 1.0 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1889017

Summary PubMed Citation Related BioAssays by Target

Select item 18839418.

Inhibition of PKL12 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1883941

Summary PubMed Citation Related BioAssays by Target

Select item 18800589.

Inhibition of MPSK1 (unknown origin) at 1 uM by kinase-profiling analysis

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1880058

Summary PubMed Citation Related BioAssays by Target

Select item 188004310.

Inhibition of MPSK1 (unknown origin) by biochemical assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1880043

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 183545111.

STK16 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1835451

Summary Related BioAssays by Target

Select item 183516412.

STK16(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1835164

Summary Related BioAssays by Target

Select item 183433113.

Inhibition of STK16 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1834331

Summary PubMed Citation Related BioAssays by Target

Select item 182376914.

Inhibition of human STK16 in presence of [gamma-33P-ATP] by radiometric scintillation assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1823769

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 180171415.

Invitrogen SelectScreen Enzymatic Assay from Article 10.1021/acschembio.6b00250: "Discovery of a Highly Selective STK16 Kinase Inhibitor."

Source:: BindingDB

Protein Targets:: Phosphatidylinositol 3-kinase catalytic subunit type 3; ...
Total:: 11

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1801714

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 179434916.

KinomeScan assay: inhibition of STK16

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:2 Active, 108 Tested

AID:: 1794349

Summary Compounds, Active Related BioAssays by Target

Select item 179390317.

MPSK1(ST16LGF1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793903

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179248918.

TSF1 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1792489

Summary Related BioAssays by Target

Select item 179119119.

STK16 (PKL12) Kinase screen

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1791191

Summary Related BioAssays by Target

Select item 179037120.

STK16 Invitrogen selectivity data (BI)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 16

Assay data:1 Tested

AID:: 1790371

Summary Related BioAssays by Target

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Target

Proteins (4)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (29)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (23)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (29)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (146)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (119)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (68)
BioAssays deposited by other experimentalists

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