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Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in phalloidin-labeled actin ring formation at 5 to 10 uM preincubated with RANKL for 1 hr followed by cell addition and subsequent media replenishment every 48 hrs for 4 days by Alexa Fluor 488-conjugated phalloidin/DAPI-staining based fluorescence microscopic analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of RANKL (unknown origin) in RANKL cultured mouse RAW264.7 cells assessed as reduction in RANKL/RANK-interaction mediated NFATc1 expression at 2 to 10 uM preincubated for 1 hr followed by cell culture addition and measured after 2 days by Western blot analysis
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