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RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Binding affinity to FUBP1 in human NCI-H23 cells at 1 uM by mass spectrometry based pull down assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to recombinant GST tagged FUBP1 KH3-KH4 domain (unknown origin) assessed as decrease in FUBP1-FUSE DNA bound complex using 5'-IRDye700 tagged TATTCCCTGATTTTT oligonucleotide as substrate measured for 30 mins by Gel shift assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of FUBP1 in human Hep3B cells assessed as upregulation of BIK mRNA expression at 10 uM after 6 hrs by qRT-PCR analysis
Assay data:2 Tested
Inhibition of FUBP1 in human Hep3B cells assessed as upregulation of p21 mRNA expression at 10 uM after 6 hrs by qRT-PCR analysis
Assay data:2 Active, 2 Tested
Inhibition of human full length FUBP1 expressed in Escherichia coli BL21 DE3 assessed as reduction in FUBP1 interaction with FUSE BIK oligonucleotide at 100 uM incubated for 21 hrs by Alphascreen assay relative to DMSO
Inhibition of human full length FUBP1 expressed in Escherichia coli BL21 DE3 assessed as reduction in FUBP1 interaction with FUSE p21 oligonucleotide at 100 uM incubated for 21 hrs by Alphascreen assay relative to DMSO
Assay data:4 Tested
Inhibition of full length 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized FUSE p21 oligonucleotide by measuring time taken for association at 100 uM incubated for 21 hrs by SPR analysis
Inhibition of 6xHis-tagged human FUBP1 expressed in HEK293T cells assessed as reduction in FUBP1 interaction with biotinylated NLC chip immobilized FUSE p21 oligonucleotide by measuring time taken for dissociation at 100 uM incubated for 21 hrs by SPR analysis
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