BioAssay by Target (List) for Gene (Select 8942) - PubChem BioAssay - NCBI

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Select item 4126461.

Ratio of kcat to Km for human kynureninase S332G/N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412646

Summary PubMed Citation Related BioAssays by Target

Select item 19042.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 945263.

Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:3 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 94526

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 945274.

Compound was evaluated for its binding affinity against kynureninase isolated from Pseudomonas fluorescence

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Tested

AID:: 94527

Summary Related BioAssays by Target

Select item 945285.

Compound was tested for the binding affinity against bacterial kynureninase

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94528

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 945296.

Tested for binding affinity against kynureninase enzyme from human

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94529

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 945357.

Tested for binding affinity against kynureninase enzyme from bacterial cells

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Active, 1 Tested

AID:: 94535

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 4126378.

Activity of human wild type kynureninase

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412637

Summary PubMed Citation Related BioAssays by Target

Select item 4126389.

Inhibition of human kynureninase at 1 mM

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412638

Summary PubMed Citation Related BioAssays by Target

Select item 41263910.

Inhibition of human kynureninase

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 412639

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 41264011.

Activity of human kynureninase N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412640

Summary PubMed Citation Related BioAssays by Target

Select item 41264112.

Activity of human kynureninase S332G/N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412641

Summary PubMed Citation Related BioAssays by Target

Select item 41264213.

Activity of human kynureninase H102W/N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Tested

AID:: 412642

Summary PubMed Citation Related BioAssays by Target

Select item 41264314.

Activity of human kynureninase H102W/S332G/N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Tested

AID:: 412643

Summary PubMed Citation Related BioAssays by Target

Select item 41264415.

Ratio of kcat to Km for human wild type kynureninase

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412644

Summary PubMed Citation Related BioAssays by Target

Select item 41264516.

Ratio of kcat to Km for human kynureninase N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412645

Summary PubMed Citation Related BioAssays by Target

Select item 150858817.

RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:790 Active, 18119 Tested

AID:: 1508588

Select item 41264718.

Ratio of kcat to Km for human kynureninase H102W/N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412647

Summary PubMed Citation Related BioAssays by Target

Select item 41264819.

Ratio of kcat to Km for human kynureninase H102W/S332G/N333T mutant

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:2 Tested

AID:: 412648

Summary PubMed Citation Related BioAssays by Target

Select item 49935520.

Inhibition of kynureninase in human prefrontal cortex homogenates at 100 uM

Source:: ChEMBL

Protein Target:: Kynureninase

Assay data:1 Tested

AID:: 499355

Summary PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (5)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (5)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (4)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (11)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (8)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (20)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (12)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (20)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (11)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 8942) (32)
PubChem BioAssay
Protein Links for Nucleotide (Select 1936180902) (285)
Protein
microtubule-associated protein 2 isoform 7 [Homo sapiens]
microtubule-associated protein 2 isoform 7 [Homo sapiens]
gi|1770726331|ref|NP_001362433.1|

Protein
PREDICTED: Homo sapiens microtubule associated protein 2 (MAP2), transcript vari...
PREDICTED: Homo sapiens microtubule associated protein 2 (MAP2), transcript variant X19, mRNA
gi|2217328053|ref|XM_024452907.2|

Nucleotide
microtubule-associated protein 2 isoform X11 [Homo sapiens]
microtubule-associated protein 2 isoform X11 [Homo sapiens]
gi|1370477712|ref|XP_024308670.1|

Protein

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