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Inhibition of human Alexa 488 labeled Arno Sec7 domain-mediated promiscuous aggregator activity in delta17 Arf1 (17 to 181) at >20 uM by fluorescence anisotropy assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Inhibition of wild type ARNO activation
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of human Arno Sec7 domain binding to immobilized delta17 Arf1 (17 to 181) at 1 mM after 15 mins by BODIPY-GTP based time resolved fluorescence assay relative to control
Assay data:2 Tested
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) at 1 mM by BODIPY-GTP based time resolved fluorescence assay relative to control
Assay data:6 Tested
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip after 15 mins by 1H 1D-NMR-700 MHz spectra analysis
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip at 250 uM by surface plasmon resonance analysis
Assay data:5 Active, 6 Tested
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip at 1 mM after 15 mins by 1H 1D-NMR-700 MHz spectra analysis
Assay data:7 Active, 10 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Inhibition of human Alexa 488 labeled Arno Sec7 domain-mediated promiscuous aggregator activity in delta17 Arf1 (17 to 181) at 100 uM by fluorescence anisotropy assay
Inhibition of human Alexa 488 labeled Arno Sec7 domain-mediated promiscuous aggregator activity in delta17 Arf1 (17 to 181) at 1 to 100 uM by fluorescence anisotropy assay
Assay data:4 Tested
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay
Assay data:11 Tested
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) assessed as residual activity at 2 mM by BODIPY-GTP based time resolved fluorescence polarization assay relative to control
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) at 2 mM by BODIPY-GTP based time resolved fluorescence assay relative to control
Assay data:8 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
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