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Human OX1 receptor (Orexin receptors)
Assay data:24 Active, 24 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Rat OX1 receptor (Orexin receptors)
Assay data:2 Active, 2 Tested
Late stage assay for the probe development effort for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:25 Active, 10 Activity ≤ 1 µM, 28 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage assay for the probe development effort for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Fluorescence-based cell-based dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:10 Active, 28 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based dose response assay for antagonists of the orexin 2 receptor (OX2R; HCRTR2), run by assay provider
Assay data:51 Active, 12 Activity ≤ 1 µM, 213 Tested
Counterscreen assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1): Fluorescence-based cell-based dose response assay for antagonists of the orexin 2 receptor (OX2R; HCRTR2), run by assay provider
Assay data:25 Active, 1 Activity ≤ 1 µM, 213 Tested
Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:228 Active, 75 Activity ≤ 1 µM, 247 Tested
Fluorescence-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:161 Active, 9 Activity ≤ 1 µM, 247 Tested
Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based high throughput assay for antagonists of the parental CHO cell line, in triplicate
Assay data:102 Active, 1095 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput confirmation assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:883 Active, 1807 Tested
Fluorescence-based cell-based high throughput confirmation assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:421 Active, 1095 Tested
FRET-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:5750 Active, 326136 Tested
Summary of the probe development effort to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1)
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based assay to identify antagonists of the parental CHO cell line
Assay data:2041 Active, 326136 Tested
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the orexin 1 receptor (OX1R; HCRTR1)
Assay data:1389 Active, 326136 Tested
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