Related BioAssays, by Gene Interaction (List) for PubChem BioAssay (Se - PubChem BioAssay - NCBI

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Select item 19638551.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/10/25
Hold-until Date:: 2025/05/03

AID:: 1963855

Select item 19635912.

Source:: Tox21

Deposit Date:: 2024/08/02
Hold-until Date:: 2025/08/02

AID:: 1963591

Select item 19635903.

Source:: Tox21

Deposit Date:: 2024/08/02
Hold-until Date:: 2025/08/02

AID:: 1963590

Select item 19635854.

p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: Summary

Source:: Tox21

Protein Target:: tumor suppressor p53 [Homo sapiens]

Assay data:70 Active, 12 Activity ≤ 1 µM, 9667 Tested

AID:: 1963585

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 19635845.

p53 small molecule agonists, cell-based qHTS assay: Summary

Source:: Tox21

Protein Target:: tumor suppressor p53 [Homo sapiens]

Assay data:212 Active, 41 Activity ≤ 1 µM, 9667 Tested

AID:: 1963584

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Same Project

Select item 19635836.

p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary

Source:: Tox21

Protein Target:: tumor suppressor p53 [Homo sapiens]

Assay data:103 Active, 14 Activity ≤ 1 µM, 9667 Tested

AID:: 1963583

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 19635827.

p53 small molecule agonists, cell-based qHTS assay

Source:: Tox21

Protein Target:: tumor suppressor p53 [Homo sapiens]

Assay data:87 Active, 5 Activity ≤ 1 nM, 180 Activity ≤ 1 µM, 9667 Tested

AID:: 1963582

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Same Project

Select item 19635788.

p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes

Source:: Tox21

Protein Target:: tumor suppressor p53 [Homo sapiens]

Assay data:27 Active, 44 Activity ≤ 1 µM, 9667 Tested

AID:: 1963578

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 19635779.

p53 small molecule agonists, cell-based qHTS assay with human liver microsomes

Source:: Tox21

Protein Target:: tumor suppressor p53 [Homo sapiens]

Assay data:43 Active, 55 Activity ≤ 1 µM, 9667 Tested

AID:: 1963577

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 196345210.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/06/03
Hold-until Date:: 2025/05/15

AID:: 1963452

Select item 196332211.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/09
Modify Date:: 2024/10/22
Hold-until Date:: 2025/05/03

AID:: 1963322

Select item 196332112.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/09
Modify Date:: 2024/10/22
Hold-until Date:: 2025/05/03

AID:: 1963321

Select item 196325213.

Cross screening panel

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lck

Assay data:1 Tested

AID:: 1963252

Summary Related BioAssays by Target

Select item 196320414.

Cross screening panel

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lck

Assay data:1 Tested

AID:: 1963204

Summary Related BioAssays by Target

Select item 196315415.

Cross screening panel

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lck

Assay data:1 Tested

AID:: 1963154

Summary Related BioAssays by Target

Select item 196307816.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Glucocorticoid receptor

Assay data:1 Tested

AID:: 1963078

Summary Related BioAssays by Target

Select item 196307717.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Glucocorticoid receptor

Assay data:1 Tested

AID:: 1963077

Summary Related BioAssays by Target

Select item 196307618.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Androgen receptor

Assay data:1 Tested

AID:: 1963076

Summary Related BioAssays by Target

Select item 196307519.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Androgen receptor

Assay data:1 Tested

AID:: 1963075

Summary Related BioAssays by Target

Select item 196307220.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lck

Assay data:1 Tested

AID:: 1963072

Summary Related BioAssays by Target

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Target

Proteins (537)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (5)
BioAssays with compounds reported as validated chemical probes

Active Compounds (20,609)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1,627)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (11,451)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (60)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (16,364)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (94)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
On Hold (6)
On hold BioAssays

Assay Project (401)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (39,675)
BioAssays extracted from the literature
NIH MLP (417)
BioAssays deposited by the NIH Molecular Libraries Program
Other (3,734)
BioAssays deposited by other experimentalists

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Related BioAssays, by Gene Interaction (List) for PubChem BioAssa... (43830)
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PubChem BioAssay
Profile neighbors for GEO Profiles (Select 42403340) (199)
GEO Profiles
Related DataSets for GEO Profiles (Select 104968121) (1)
GEO DataSets
Cediranib effect on metastatic alveolar soft part sarcoma
Cediranib effect on metastatic alveolar soft part sarcoma
Accession: GDS4833

GEO DataSets
PREDICTED: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta...
PREDICTED: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [Apaloderma vittatum]
gi|699605879|ref|XP_009871753.1|

Protein

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