Related BioAssays, by Gene Interaction (List) for PubChem BioAssay (Se - PubChem BioAssay - NCBI

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Select item 19635411.

ADP-Glo Kinase Assay from US Patent US20240101538: "PROTEIN-PROTEIN INTERACTION MODULATORS OF AURORA KINASE A AND THEIR USE IN THE PREVENTION AND/OR TREATMENT OF CANCER"

Source:: BindingDB

Protein Targets:: Aurora kinase A; ...
Total:: 1

Assay data:3 Active, 3 Activity ≤ 1 µM, 10 Tested

AID:: 1963541

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19634522.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/06/03
Hold-until Date:: 2025/05/15

AID:: 1963452

Select item 19629833.

DYRK1A SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Assay data:1 Tested

AID:: 1962983

Summary Related BioAssays by Target

Select item 19629634.

STK6 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Tested

AID:: 1962963

Summary Related BioAssays by Target

Select item 19629115.

MAPK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1962911

Summary Related BioAssays by Target

Select item 19628796.

DYRK1A SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Assay data:1 Tested

AID:: 1962879

Summary Related BioAssays by Target

Select item 19628597.

STK6 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Tested

AID:: 1962859

Summary Related BioAssays by Target

Select item 19628078.

MAPK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1962807

Summary Related BioAssays by Target

Select item 19627679.

STK6 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Tested

AID:: 1962767

Summary Related BioAssays by Target

Select item 196273210.

MAPK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1962732

Summary Related BioAssays by Target

Select item 196270711.

DYRK1A SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Assay data:1 Tested

AID:: 1962707

Summary Related BioAssays by Target

Select item 196266812.

STK6 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Tested

AID:: 1962668

Summary Related BioAssays by Target

Select item 196263313.

MAPK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1962633

Summary Related BioAssays by Target

Select item 196260814.

DYRK1A SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Assay data:1 Tested

AID:: 1962608

Summary Related BioAssays by Target

Select item 196242415.

MAPK1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1962424

Summary Related BioAssays by Target

Select item 196227716.

MAPK1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1962277

Summary Related BioAssays by Target

Select item 196090817.

Inhibition of Aurora A (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Tested

AID:: 1960908

Summary PubMed Citation Related BioAssays by Target

Select item 196088518.

Inhibition of ERK1 (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 3

Assay data:1 Tested

AID:: 1960885

Summary PubMed Citation Related BioAssays by Target

Select item 196087919.

Inhibition of ERK2 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1960879

Summary PubMed Citation Related BioAssays by Target

Select item 195935920.

Inhibition of PKC (unknown origin) using acetylated myelin basic protein (4 to 14 residues) as substrate incubated for [gamma-32P]-ATP incubated for 5 mins by scintillation counter analysis

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 11

Assay data:1 Tested

AID:: 1959359

Summary PubMed Citation Related BioAssays by Target

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Proteins (55)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (2)
BioAssays with compounds reported as validated chemical probes

Active Compounds (2,679)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (316)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,605)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (2,369)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (5)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (6,082)
BioAssays extracted from the literature
NIH MLP (48)
BioAssays deposited by the NIH Molecular Libraries Program
Other (2,160)
BioAssays deposited by other experimentalists

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Peripheral venous congestion model: endothelial cells
Peripheral venous congestion model: endothelial cells
Accession: GDS4773

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