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Quantitative High-Throughput Screen for Inhibitors and Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Summary
Assay data:1 Active, 5 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Quantitative High-Throughput Screen for Inhibitors of Human alpha-Galactosidase at pH 4.5: Summary
Assay data:15 Active, 15 Tested
qHTS for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Metabolic Stability in presence of NADPH
Assay data:3 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Metabolic Stability
Assay data:2 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Aqueous Solubility
Assay data:1 Active, 1 Tested
qHTS for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Fibroblast Translocation
Assay data:2 Active, 2 Tested
Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Alpha-Galactosidase Counter Screen
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Glucocerebrosidase Counter Screen
Assay data:29 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibitors of Human alpha-Glucosidase: Caco-2 Efflux Ratio Profiling
Assay data:1 Tested
Inhibitors of Human alpha-Glucosidase: Caco-2 Cell Permeability Profiling
Inhibitors of Human alpha-Glucosidase: PBS Stability Profiling
qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease: Stabilizers of Alpha-Glucosidase Under Thermal Denaturation Conditions
Assay data:10 Active, 10 Tested
Direct Measure of the Activation of Acid alpha-Glucosidase Catalytic Rate
qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease
Assay data:715 Active, 924 Activity ≤ 1 µM, 199303 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase
Assay data:19 Active, 4 Activity ≤ 1 µM, 338 Tested
Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate
Assay data:57 Active, 7 Activity ≤ 1 µM, 423 Tested
qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate
Assay data:16 Active, 90 Activity ≤ 1 µM, 236748 Tested
Confirmation of Inhibitors and Activators of Human alpha-Glucosidase From Spleen Homogenate Using an Alternate Red Fluorescent Susbtrate
Assay data:58 Active, 4 Activity ≤ 1 µM, 98 Tested
Confirmation of Inhibitors and Activators of Purified Human alpha-Glucosidase Using an Alternate Red Fluorescent Susbtrate
Assay data:57 Active, 7 Activity ≤ 1 µM, 109 Tested
Confirmation of Inhibitors and Activators of Purified Human alpha-Galactosidase
Assay data:3 Active, 402 Tested
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