Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of HIV-1 protease by FRET-based assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of HIV-1 protease relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of HIV-1 protease
Assay data:16 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 22 Tested
Binding affinity to HIV-1 protease assessed as inhibition constant
Assay data:8 Active, 2 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Potency index, ratio of darunavir Ki to test compound Ki for inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELISA analysis
Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELISA analysis
Assay data:15 Active, 12 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 15 Tested
Inhibition of recombinant HIV1 Protease using His-Lys-Ala-Arg-Val-Leu-(pNO2-Phe)-Glu-Ala-Nle-SerNH2 peptide as substrate
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of recombinant HIV1 Protease
Assay data:8 Active, 4 Activity ≤ 1 µM, 8 Tested
Inhibition of recombinant HIV1 Protease using Abz-Thr-Ile-Nle-(p-nitro)-Phe-Gln-Arg-NH2 peptide as substrate
Assay data:1 Active, 1 Tested
Inhibition of recombinant wildtype HIV1 Protease using Abz-Thr-Ile-Nle-Phe(NO2)-Gln-Arg peptide as substrate
Binding affinity to wild-type HIV1 protease expressed in Escherichia coli BL21(DE3) assessed as inhibition constant using (2-aminobenzoyl)Thr-Ile-Nle-(p-nitro)Phe-Gln-Arg peptide as substrate preincubated for 15 mins followed by substrate addition by fluorimeter analysis
Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to HIV1 protease assessed as inhibition constant
Assay data:19 Active, 8 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 20 Tested
Binding affinity to HIV1 protease assessed as inhibition constant using Val-Ser-Gln-Asn-betaNal-Pro-Ile-Val as substrate by HPLC method
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to HIV1 recombinant wild type protease expressed in Escherichia coli BL21(DE3) assessed as inhibition constant
Binding affinity to wild-type HIV1 protease expressed in Escherichia coli by fluorometric assay
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of HIV-1 protease assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Assay data:5 Active, 2 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of HIV-1 protease assessed as inhibition
Inhibition of HIV1 protease
Assay data:6 Active, 2 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on