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Safety47 Scan (DiscoverX - Eurofins)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Endothelin ETB Eurofins Panlabs panel
Endothelin ETA Eurofins Panlabs panel
ETA/H Eurofins SafetyScreen44 (BI)
Binding affinity towards human EDNRB in an in vitro assay with cellular components measured by scintillation proximity assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 298 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity towards human EDNRA in an in vitro assay with cellular components measured by scintillation proximity assay
Assay data:4 Active, 2 Activity ≤ 1 µM, 819 Tested
Displacement of [125I]-endothelin-1 from human recombinant ETA receptor at 10 uM after 120 mins by scintillation counting analysis relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to human placenta ETB
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human ETA
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
Selectivity interaction (CEREP panel (Eurofins, receptors, ion channels, and other enzymes)) EUB0000348aPTSA EDNRB
Affinity Biochemical interaction (Inhibition of 125I labeled ET-3 binding) EUB0000350a EDNRB
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Affinity Biochemical interaction ([125I]-endothelin-1 saturation binding assay) EUB0000348aPTSA EDNRA
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
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