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Drug transport in human OAT2 expressed in HEK Flp-In cells at 0.05 uM for 10 mins relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Drug transport in human OAT2 expressed in HEK Flp-In cells at 0.07 uM for 10 mins relative to control
Drug transport in human OAT2 expressed in HEK Flp-In cells at 0.19 uM for 10 mins relative to control
Drug transport in human OAT2 expressed in HEK Flp-In cells at 0.06 uM for 10 mins relative to control
Drug uptake assessed as OAT2 (unknown origin)-mediated drug transport expressed in HEK293 cells by LC-MS/MS analysis relative to control
Assay data:2 Tested
TP_TRANSPORTER: inhibition of Salicylate uptake in Oat2-expressing LLC PK1 cells
Assay data:2 Active, 3 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
TP_TRANSPORTER: uptake in Xenopus laevis oocytes
Assay data:7 Tested
Assay data:1 Active, 1 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, BSP: 250 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, Cefoperazone: 1000 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, Cimetidine: 1000 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, Enalapril: 1000 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, Erythromycin: 1000 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, ICG: 1000 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of Glutarate uptake (Glutarate: 5 uM, Oxaloacetate: 1000 uM) in Xenopus laevis oocytes
TP_TRANSPORTER: inhibition of PAH uptake (BSP: 100 uM) in OAT2-expressing EcR293 cells
TP_TRANSPORTER: inhibition of PAH uptake (alpha-KG: 500 uM) in OAT2-expressing EcR293 cells
TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2alpha: 0.005 uM, AZT: 1000 uM) in OAT2-expressing S2 cells
TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2alpha: 0.005 uM, GCV: 1000 uM) in OAT2-expressing S2 cells
TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2alpha: 0.005 uM, Minocycline: 5 uM) in OAT2-expressing S2 cells
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