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Panlabs assay PDE10A2
Assay data:1 Tested
SummaryRelated BioAssays by Target
3H-cAMP and 3H-cGMP Scintillation Proximity Assay (PDE10A)
Inhibition of full-length recombinant human PDE10A by scintillation proximity assay
Assay data:6 Active, 4 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PDE10A2 (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human recombinant PDE10A expressed in Sf9 cells incubated for 60 mins by scintillation counter analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to PDE10A in rat striatum homogenate
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to PDE10A in rat brain nucleus accumbens by saturation binding assay
Binding affinity to PDE10A in rat brain caudate-putamen by saturation binding assay
Inhibition of PDE10A (unknown origin) by scintillation proximity assay
Inhibition of PDE10A (unknown origin)
Assay data:18 Active, 5 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 18 Tested
Inhibition of human PDE10A (449 to 789 residues) expressed in Escherichia coli BL21(DE3) using cAMP as substrate at 4 uM incubated for 30 mins by HTRF analysis relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human PDE10A (449 to 789 residues) expressed in Escherichia coli BL21(DE3) using cAMP as substrate incubated for 30 mins by HTRF analysis
Binding affinity to PDE10A (unknown origin) assessed as dissociation constant
Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to full length human PDE10A assessed as dissociation constant
Binding affinity to full length human PDE10A assessed as dissociation constant using [3H]-cAMP as substrate
Assay data:9 Active, 5 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of human PDE10A
Assay data:2 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of rat PDE10A
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human PDE10
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