Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Purinergic P2Y Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of human P2Y1 by FLIPR assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human P2Y1 assessed as inhibition constant
Assay data:7 Active, 7 Activity ≤ 1 µM, 9 Tested
Displacement of [beta-33p]-2-MeS-ADP from human P2Y1
Assay data:13 Active, 12 Activity ≤ 1 µM, 18 Tested
Agonist activity at human P2Y1
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of human P2Y1
Antagonist activity at human P2Y1 by FLIPR assay
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Agonist activity at human P2Y1R in human 1321N1 cells assessed as efficacy relative to control
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human P2Y1R in human 1321N1 cells
Assay data:5 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 6 Tested
Antagonist activity at Meleagris P2Y1R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization at 100 uM by FLIPR assay relative to control
Assay data:5 Tested
Antagonist activity at human P2Y1 receptor assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Antagonist activity at P2Y1R (unknown origin) expressed in human 1321N1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 15 mins in presence of IBMX by chromatography
Antagonist activity at human P2Y1R expressed in HEK293 cells assessed as inhibition of ADP-induced IP3 production preincubated for 0.5 hrs followed by ADP stimulation by ELISA
Antagonist activity at P2Y1 receptor (unknown origin)
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
Binding affinity to P2Y1 receptor (unknown origin)
Displacement of [3H]2MeSADP from human P2Y1 expressed in U2OS cell membranes incubated for 60 mins by scintillation counting method
P2Y/RAT Eurofins SafetyScreen44 (BI)
Scintillation Proximity Assay (SPA) from US Patent US9428504: "7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor"
Assay data:156 Active, 156 Activity ≤ 1 µM, 156 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Binding Assay from US Patent US9428504: "7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor"
Assay data:13 Active, 12 Activity ≤ 1 µM, 13 Tested
Binding Assay from US Patent US9120798: "Amino-heteroaryl 7-hydroxy-spiropiperidine indolinyl antagonists of P2Y1 receptor"
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on