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Binding affinity to FPR2 (unknown origin) at 10 uM by radioligand binding assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human FPR2 expressed in CHO-K1 cells by beta-arrestin recruitment assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at mouse FPR3 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human FPR2 expressed in CHO cells assessed as increase in calcium flux incubated for 50 mins by FLIPR calcium 5 dye based fluorescence assay
Assay data:7 Active, 7 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human FPR2 expressed in HEK293 cells assessed as increase in calcium flux incubated for 60 mins by FLIPR assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at mouse FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Agonist activity at human FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Agonist activity at human FPR2 expressed in HEK293 cells assessed as increase in calcium flux incubated for 45 mins by Fluo-4 AM dye based fluorescence assay
Assay data:10 Active, 8 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Agonist activity at FPR2 (unknown origin) assessed as increase in calcium flux
Assay data:4 Active, 3 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Agonist activity at human FPR2 expressed in CHO cells assessed as cAMP level incubated for 1.5 hr by HTRF assay
Assay data:44 Active, 4 Activity ≤ 1 nM, 44 Activity ≤ 1 µM, 44 Tested
Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation at 10 uM incubated for 1 hr by Alphascreen fluorescence assay relative to control
Assay data:3 Tested
Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation incubated for 1 hr by Alphascreen fluorescence assay
Assay data:2 Active, 3 Tested
Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as maximal intracellular calcium mobilization at 10 uM incubated for 1 hr by Fluo-4 AM dye based fluorescence plate reader assay relative to control
Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as increase in intracellular calcium mobilization incubated for 1 hr by Fluo-4 AM dye based fluorescence plate reader assay
Agonist activity at human FPR2 transfected in HL-60 cells assessed as maximal intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based FLIPR-fluorometeric assay relative to control
Agonist activity at human FPR2 transfected in HL-60 cells assessed as increase in intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based FLIPR-fluorometeric assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Agonist activity at human FPR2 transfected in HL-60 cells assessed as maximal intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based fluorometer analysis relative to control
Assay data:6 Tested
Agonist activity at human FPR2 transfected in HL-60 cells assessed as increase in intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based fluorometer analysis
Assay data:8 Active, 3 Activity ≤ 1 µM, 10 Tested
Agonist activity at FPR2 (unknown origin) expressed in CHO/Galpha16 cells assessed as maximal calcium flux at 0.61 to 10000 nM by FLIPR assay relative to control
Assay data:5 Tested
Agonist activity at FPR2 (unknown origin) expressed in CHO/Galpha16 cells assessed as increase in calcium flux by FLIPR assay
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
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