Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19479141.

Binding affinity to FPR2 (unknown origin) at 10 uM by radioligand binding assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:1 Tested

AID:: 1947914

Summary PubMed Citation Related BioAssays by Target

Select item 19322392.

Agonist activity at human FPR2 expressed in CHO-K1 cells by beta-arrestin recruitment assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:1 Active, 1 Tested

AID:: 1932239

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19322383.

Agonist activity at mouse FPR3 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: Formyl peptide receptor-related sequence 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1932238

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322374.

Agonist activity at human FPR2 expressed in CHO cells assessed as increase in calcium flux incubated for 50 mins by FLIPR calcium 5 dye based fluorescence assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:7 Active, 7 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 7 Tested

AID:: 1932237

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322355.

Agonist activity at human FPR2 expressed in HEK293 cells assessed as increase in calcium flux incubated for 60 mins by FLIPR assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1932235

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322266.

Agonist activity at mouse FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: Formyl peptide receptor 2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1932226

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322247.

Agonist activity at human FPR2 expressed in CHO-A12 cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1932224

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322198.

Agonist activity at human FPR2 expressed in HEK293 cells assessed as increase in calcium flux incubated for 45 mins by Fluo-4 AM dye based fluorescence assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:10 Active, 8 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested

AID:: 1932219

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19322189.

Agonist activity at FPR2 (unknown origin) assessed as increase in calcium flux

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:4 Active, 3 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1932218

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221610.

Agonist activity at human FPR2 expressed in CHO cells assessed as cAMP level incubated for 1.5 hr by HTRF assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:44 Active, 4 Activity ≤ 1 nM, 44 Activity ≤ 1 µM, 44 Tested

AID:: 1932216

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193221411.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation at 10 uM incubated for 1 hr by Alphascreen fluorescence assay relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Tested

AID:: 1932214

Summary PubMed Citation Related BioAssays by Target

Select item 193221212.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation incubated for 1 hr by Alphascreen fluorescence assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:2 Active, 3 Tested

AID:: 1932212

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193221013.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as maximal intracellular calcium mobilization at 10 uM incubated for 1 hr by Fluo-4 AM dye based fluorescence plate reader assay relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Tested

AID:: 1932210

Summary PubMed Citation Related BioAssays by Target

Select item 193220814.

Agonist activity at human recombinant FPR2 stably transfected in Flp-In-CHO cells assessed as increase in intracellular calcium mobilization incubated for 1 hr by Fluo-4 AM dye based fluorescence plate reader assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Tested

AID:: 1932208

Summary PubMed Citation Related BioAssays by Target

Select item 193220315.

Agonist activity at human FPR2 transfected in HL-60 cells assessed as maximal intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based FLIPR-fluorometeric assay relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Tested

AID:: 1932203

Summary PubMed Citation Related BioAssays by Target

Select item 193220116.

Agonist activity at human FPR2 transfected in HL-60 cells assessed as increase in intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based FLIPR-fluorometeric assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1932201

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193219917.

Agonist activity at human FPR2 transfected in HL-60 cells assessed as maximal intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based fluorometer analysis relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:6 Tested

AID:: 1932199

Summary PubMed Citation Related BioAssays by Target

Select item 193219718.

Agonist activity at human FPR2 transfected in HL-60 cells assessed as increase in intracellular calcium flux incubated for 30 mins by Fluo-4 AM dye based fluorometer analysis

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:8 Active, 3 Activity ≤ 1 µM, 10 Tested

AID:: 1932197

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193219519.

Agonist activity at FPR2 (unknown origin) expressed in CHO/Galpha16 cells assessed as maximal calcium flux at 0.61 to 10000 nM by FLIPR assay relative to control

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:5 Tested

AID:: 1932195

Summary PubMed Citation Related BioAssays by Target

Select item 193219320.

Agonist activity at FPR2 (unknown origin) expressed in CHO/Galpha16 cells assessed as increase in calcium flux by FLIPR assay

Source:: ChEMBL

Protein Target:: N-formyl peptide receptor 2

Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1932193

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Proteins (19)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (1)
BioAssays with compounds reported as validated chemical probes

Active Compounds (114)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (29)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (84)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (96)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (5)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (9)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (179)
BioAssays extracted from the literature
NIH MLP (9)
BioAssays deposited by the NIH Molecular Libraries Program
Other (6)
BioAssays deposited by other experimentalists

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