Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 18290041.

Activation of GLP2 receptor transfected in human HEK293 cells assessed as increase in intracellular cAMP level at 1 nM

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:1 Active, 2 Tested

AID:: 1829004

Summary Compounds, Active Related BioAssays by Target

Select item 18289742.

Binding affinity towards GLP-2 receptor in human HEK293 cells measured by fluorescence assay

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:9 Active, 3 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested

AID:: 1828974

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 17917413.

PRESTO-Tango GPCRome screening (GLP2R)

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:1 Tested

AID:: 1791741

Summary Related BioAssays by Target

Select item 15801074.

Agonist activity at human GLP-2 receptor expressed in CHO-K1 cells assessed as cAMP induction by FRET assay

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1580107

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 14113545.

Agonist activity at human GLP2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP accumulation by AlphaScreen assay

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:14 Active, 13 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 15 Tested

AID:: 1411354

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 13631866.

Antagonist activity at GLP2R (unknown origin) at 10 uM by cAMP accumulation based assay relative to control

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:1 Tested

AID:: 1363186

Summary PubMed Citation Related BioAssays by Target

Select item 13631857.

Agonist activity at GLP2R (unknown origin) at 10 uM by cAMP accumulation based assay relative to control

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:1 Tested

AID:: 1363185

Summary PubMed Citation Related BioAssays by Target

Select item 13459368.

Rat GLP-2 receptor (Glucagon receptor family)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: glucagon-like peptide 2 receptor

Assay data:6 Active, 6 Tested

AID:: 1345936

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 13459299.

Human GLP-2 receptor (Glucagon receptor family)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: glucagon-like peptide 2 receptor

Assay data:4 Active, 4 Tested

AID:: 1345929

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 130970810.

Agonist activity at rat GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1309708

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 130970011.

Potency index, ratio of compound EC50 to compound 2 EC50 for human GLP2R expressed in HEK293 cells

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:29 Tested

AID:: 1309700

Summary PubMed Citation Related BioAssays by Target

Select item 130969812.

Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:93 Active, 79 Activity ≤ 1 nM, 95 Activity ≤ 1 µM, 95 Tested

AID:: 1309698

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 70840313.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as reduction of GLP2-induced cAMP level at 3 to 10 uM after 30 mins

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:1 Tested

AID:: 708403

Summary PubMed Citation Related BioAssays by Target

Select item 70840214.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation at 50 uM measured on day 3 by Alamar Blue assay relative to 100 pM GLP2

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:8 Tested

AID:: 708402

Summary PubMed Citation Related BioAssays by Target

Select item 70840115.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation at 25 uM measured on day 3 by Alamar Blue assay relative to 10 pM GLP2

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:28 Tested

AID:: 708401

Summary PubMed Citation Related BioAssays by Target

Select item 70840016.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation at 50 uM measured on day 3 by Alamar Blue assay relative to 10 pM GLP2

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:7 Tested

AID:: 708400

Summary PubMed Citation Related BioAssays by Target

Select item 70839917.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation at 25 uM measured on day 3 by Alamar Blue assay relative to 100 pM GLP2

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:38 Tested

AID:: 708399

Summary PubMed Citation Related BioAssays by Target

Select item 70839818.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation measured on day 3 by Alamar Blue assay

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:3 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 19 Tested

AID:: 708398

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 70839719.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation at 12.5 uM measured on day 3 by Alamar Blue assay relative to 100 pM GLP2

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:12 Tested

AID:: 708397

Summary PubMed Citation Related BioAssays by Target

Select item 70839620.

Positive ago-allosteric modulation of GLP2R overexpressed in human SE302 cells assessed as placental alkaline phosphatase activation at 6.3 uM measured on day 3 by Alamar Blue assay relative to 10 pM GLP2

Source:: ChEMBL

Protein Target:: Glucagon-like peptide 2 receptor

Assay data:2 Tested

AID:: 708396

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (16)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (6)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (6)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (6)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (43)
BioAssays extracted from the literature
Other (4)
BioAssays deposited by other experimentalists

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GSE44834[ACCN] AND gsm[ETYP] (13)
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