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Human RB binding protein 9, serine hydrolase (3.1.1.- Carboxylic Ester Hydrolases)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of FP-Rh probe binding to RBBP9 (unknown origin) at 685 nM incubated for 30 mins followed by FP-Rh probe addition measured after 30 mins by ABPP gel-based assay
Inhibition of FP-Rh probe binding to RBBP9 (unknown origin) at 100 uM incubated for 30 mins followed by FP-Rh probe addition measured after 30 mins by ABPP gel-based assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Rbbp9 in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC assay
Assay data:3 Tested
Late stage assay provider results from the probe development effort to identify inhibitors of diacylglycerol lipase, beta (DAGLb): LCMS-based cell-based Activity-Based Protein Profiling (ABPP) SILAC selectivity analysis for ABHD6
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage assay provider results from the probe development effort to identify inhibitors of PME-1: ABHD10 inhibitor LC-MS/MS-based cell-based ABPP-SILAC assay
Late stage assay provider results from the probe development effort to identify inhibitors of PME-1: LC-MS/MS-based cell-based ABPP-SILAC assay
Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome
Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome
Displacement of fluorophosphate-rhodamine from recombinant RBBP9 transfected in mouse brain membrane proteomes at 200 uM after 30 mins by SDS-PAGE gel fluorescence assay
Displacement of fluorophosphate-rhodamine from recombinant RBBP9 transfected in mouse brain membrane proteomes after 30 mins by SDS-PAGE gel fluorescence assay
Displacement of phenylsulphonate-rhodamine from RBBP9 transfected in human MDA-MB-231 cells proteomes after 30 mins by SDS-PAGE gel fluorescence assay
Displacement of fluorophosphate-rhodamine from RBBP9 transfected in human HEK293T cells proteomes at 7.9 uM after 30 mins by SDS-PAGE gel fluorescence assay
Assay data:4 Tested
Displacement of fluorophosphate-rhodamine from RBBP9 transfected in human HEK293T cells proteomes at 20 uM after 30 mins by SDS-PAGE gel fluorescence assay
Assay data:24 Tested
Displacement of fluorophosphate-rhodamine from RBBP9 transfected in human HEK293T cells proteomes after 30 mins by SDS-PAGE gel fluorescence assay
Assay data:7 Active, 1 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Summary of probe development efforts to identify inhibitors of Retinoblastoma binding protein 9 (RBBP9): Ester Oxime Scaffold
Late stage results from the probe development effort to identify inhibitors of Retinoblastoma Binding Protein 9 (RBBP9): Gel-based Activity-Based Protein Profiling (ABPP) Inhibition
Assay data:13 Active, 37 Tested
Late stage results from the probe development effort to identify inhibitors of Retinoblastoma Binding Protein 9 (RBBP9): Gel-based Activity-Based Protein Profiling (ABPP) IC50
Assay data:5 Active, 1 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage results from the probe development effort to identify inhibitors of Retinoblastoma Binding Protein 9 (RBBP9): Gel-based Activity-Based Protein Profiling (ABPP) Gel Filtration Assay
Summary of probe development efforts to identify inhibitors of Retinoblastoma binding protein 9 (RBBP9).
Assay data:2 Active, 5 Tested
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