Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
FRET Assay for REV-ERB Ligands from US Patent US20240002380: "REV-ERB AGONISTS"
Assay data:20 Active, 20 Activity ≤ 1 µM, 26 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Human Rev-Erb-beta (1D. Rev-Erb receptors)
Assay data:5 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of REV-ERBbeta in human LNCAP cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method
Assay data:1 Active, 1 Tested
Inhibition of REV-ERBbeta in human HepG2 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method
Inhibition of REV-ERBbeta in human SKBR3 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method
Inhibition of REV-ERBbeta in human BT474 cells assessed as reduction in BMAL1 expression at 10 uM incubated for 16 hrs by immunoblot method
Assay data:4 Active, 4 Tested
Inhibition of REV-ERBbeta (unknown origin) expressed in HEK293 cells incubated for 24 hrs assessed as inhibition of receptor-mediated transcriptional repression by REV-ERB luciferase reporter assay
Assay data:3 Active, 4 Tested
Increased REV-ERB-beta LBD dependent repressor activity in HEK293 cell reporter assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Late stage assay provider results from the probe development effort to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Center Based Initiative to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR): luminescence-based high throughput cell-based assay to identify modulators of human nuclear receptors.
Assay data:14 Active, 14 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on