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Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Safety47 Scan (DiscoverX - Eurofins)
Cholinesterase, Acetyl, ACES Eurofins Panlabs panel
Compound was evaluated for inhibition of human ACHE in an vitro cell free assay measured by absorbance method
Assay data:10 Active, 5 Activity ≤ 1 µM, 73 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Assay data:31 Active, 15 Activity ≤ 1 µM, 927 Tested
Inhibition of AChE (unknown origin) upto 10000 nM
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of AChE (unknown origin) by UV spectrophotometric analysis
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of AChE (unknown origin)
Assay data:13 Active, 13 Activity ≤ 1 µM, 14 Tested
Inhibition of human AchE
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured for 5 mins by Ellman's spectrophotometric method
Assay data:19 Active, 5 Activity ≤ 1 µM, 20 Tested
Competitive inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by varing concentrations of substrate addition and measured for 5 mins by Lineweaver-Burk plot analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with compounds for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method relative to control
Assay data:4 Active, 2 Activity ≤ 1 µM, 6 Tested
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate at 50 uM preincubated with compounds for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method relative to control
Assay data:5 Tested
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate at 50 to 100 uM preincubated with compounds for 20 mins followed by substrate addition and measured after 20 mins by Ellman's method relative to control
Assay data:12 Tested
Inhibition of Electrophorus electricus AChE at 100 uM using acetylcholine iodide as substrate incubated for 29 mins by Ellman's method relative to control
Inhibition of human erythrocyte AChE incubated for 10 mins by Ellman's method
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