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Binding affinity to PHB2 in human HBL cells assessed as upregulation of ERK phosphorylation at 1 to 10 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to PHB2 in human HL60 cells assessed as upregulation of ERK phosphorylation at 0.1 uM after 24 hrs by Western blot analysis
Assay data:2 Active, 2 Tested
Binding affinity to PHB2 in human HL60 cells assessed as LC3-2 accumulation at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB2 in human HL60 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as upregulation of tyrosinase protein expression at 1 to 10 uM after 24 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as upregulation of MITF protein expression at 1 to 10 uM after 24 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as LC3-2 accumulation at 1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB2 in human MM162 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB2 in human MM043 cells at 0.1 to 10 uM after 24 hrs by Western blot analysis
Downregulation of PHB2 in human HBL cells at 0.1 to 10 uM after 24 to 48 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as feedback mechanism based inhibition of ERK phosphorylation at 0.1 to 10 uM after 48 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as upregulation of ERK phosphorylation at 0.1 to 10 uM after 24 hrs by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as LC3-2 accumulation at 10 uM after 24 in presence of autophagy activator HD1 by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as LC3-2 accumulation at 10 uM after 24 in presence of autophagy inhibitor PIK-3 by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to PHB2 in human HBL cells assessed as upregulation of MITF protein expression at 10 uM after 24 in presence of autophagy activator HD1 by Western blot analysis
Binding affinity to PHB2 in human HBL cells assessed as upregulation of MITF protein expression at 10 uM after 24 in presence of autophagy inhibitor PIK-3 by Western blot analysis
Induction of PHB2-mediated melanogenesis in human HBL cells assessed as pigmentation at 10 uM after 10 days in presence of autophagy activator HD1
Induction of PHB2-mediated melanogenesis in human HBL cells assessed as pigmentation at 10 uM after 10 days in presence of autophagy inhibitor PIK-3
Binding affinity to PHB2 in human HBL cells assessed as LC3-2 accumulation after 24 to 48 hrs by Western blot analysis
Assay data:2 Tested
Binding affinity to PHB2 in human HBL cells assessed as upregulation of tyrosinase protein expression at 0.1 to 10 uM after 24 to 48 hrs by Western blot analysis
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