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Human nicotinic acetylcholine receptor alpha7 subunit (Nicotinic acetylcholine receptors)
Assay data:27 Active, 27 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of [3H]IMI binding to Drosophila melanogaster neuronal acetylcholine receptor
Assay data:8 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [3H]IMI from nicotinic acetylcholine receptor in Aphis craccivora (cowpea aphid) whole body membrane after 90 min by filter binding assay
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Displacement of [3H]IMI from nicotinic acetylcholine receptor in Drosophila melanogaster head membrane after 90 min by filter binding assay
Assay data:14 Active, 14 Activity ≤ 1 µM, 16 Tested
Competitive inhibition of nicotinic acetylcholine receptor in Drosophila melanogaster head membrane using [3H]IMI as substrate incubated for 5 min prior to substrate addition measured after 90 min by Sctachard plot analysis
Assay data:2 Active, 2 Tested
Inhibition of Drosophila melanogaster AChE by colorimetric method
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to Drosophila brain nicotinic acetylcholine receptor assessed as [3H]IMI binding by radioligand binding assay
Assay data:8 Active, 1 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 8 Tested
Inhibition of adult Drosophila melanogaster AChE by colorimetric method
Assay data:3 Active, 5 Tested
Binding affinity to Laodelphax striatella (small brown planthopper) nicotinic acetylcholine receptor
Assay data:34 Active, 34 Tested
Binding affinity to Nephotettix cincticeps (green rice leafhopper) nicotinic acetylcholine receptor
Antagonist activity at nAChR in Heliothis virescens neuronal cells assessed as blockade of acetylcholine-induced response at 10 uM by voltage clamp technique
Assay data:1 Tested
Antagonist activity at nAChR in Heliothis virescens neuronal cells by voltage clamp technique
Assay data:1 Active, 1 Tested
Agonist activity at nAChR in Heliothis virescens neuronal cells by voltage clamp technique
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Binding affinity for nAChR with [3H]imidacloprid in Myzus persicae
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Binding affinity for nAChR with [3H]imidacloprid in Drosophila
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
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