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Diamine Oxidase (DAO) Selectivity Assay from US Patent US10807974: "Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer"
Assay data:12 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
DAO Inhibition Assay from US Patent US9302986: "Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof"
Assay data:12 Active, 16 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of recombinant human DAO assessed as reduction of H2O2 production from oxidative deamination of DAP at 10 uM preincubated for 2 hrs followed by substrate addition measured every 2 mins for 1 hr by amplex red reagent-based fluorescence assay
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of porcine kidney DAO using [1,4-14C]-putrescine as substrate preincubated for 30 mins followed by substrate addition
Assay data:17 Tested
Inhibition of pig kidney DAO at 100 uM
Assay data:2 Tested
Inhibition of pig kidney DAO at 50 uM
Assay data:1 Tested
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of putrescine binding to Diamine oxidase of porcine kidney
Vmax for Diamine oxidase of porcine kidney
Inhibition of putrescine binding to against Diamine oxidase of porcine kidney
Assay data:9 Active, 6 Activity ≤ 1 µM, 21 Tested
Km for Diamine oxidase of porcine kidney
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Compound was tested for inhibition of Diamine oxidase (DAO); Inactive
In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.
Assay data:15 Active, 4 Activity ≤ 1 µM, 22 Tested
Inhibitory activity against Swine kidney diamine oxidase (SKDAO); No inhibition, corresponding to value >10e-4
Inhibitory activity against Swine kidney diamine oxidase (SKDAO)
Assay data:2 Active, 4 Tested
Tested for ability to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay
Assay data:5 Active, 3 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In vitro inhibition against hog kidney diamine oxidase
Assay data:1 Active, 1 Tested
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