Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of human ANO2 expressed in HEK293 cells incubated for 5 mins by whole cell patch clamp electrophysiology
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of YFP tagged ANO1 (unknown origin) expressed in FRT cells at 30 uM incubated for 24 hrs by whole cell patch clamp electrophysiology relative to control
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human ANO2 expressed in HEK293 cells at 30 uM incubated for 5 mins by whole cell patch clamp electrophysiology relative to control
Inhibition of YFP tagged ANO1 (unknown origin) expressed in FRT cells incubated for 24 hrs by fluorescence plate reader assay
Assay data:23 Active, 8 Activity ≤ 1 µM, 36 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of mouse TMEM16A at 10 uM measured by cell-based fluorescence assay
Assay data:1 Tested
SummaryRelated BioAssays by Target
Automated Whole-Cell Patch Clamp Assay from US Patent US11364246: "Compounds"
Assay data:229 Active, 193 Activity ≤ 1 µM, 229 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of ANO1 Over ANO2 from US Patent US11274074: "Pharmaceutical composition for ANO1 antagonist with anticancer activity"
Assay data:4 Active, 4 Activity ≤ 1 µM, 34 Tested
Automated Whole-Cell Patch Clamp Assay to Detect TMEM16A Activity in Recombinant Cells from US Patent US20200361871: "COMPOUNDS"
Inhibition of human ANO1 expressed in FRT cells assessed as inhibition of ATP-induced channel current treated 20 mins prior to ATP challenge and measured by pacth-clamp technique
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of ANO1 channel (unknown origin)
Inhibition of GFP-fused mouse ANO2 channel expressed in HEK293A cells assessed as inhibition of channel current amplitude at membrane potential of +80 mV by patch clamp electrophysiology assay
Assay data:1 Active, 2 Tested
Inhibition of ANO1 in human U251 cells assessed as inhibition of channel current at 10 uM by patch clamp electrophysiology assay
Assay data:2 Tested
Irreversible inhibition of GFP-fused mouse ANO1 channel expressed in HEK293A cells assessed as inhibition of channel current amplitude at 10 uM at membrane potential of +80 mV measured after drug wash-out by patch clamp electrophysiology assay
Reversible inhibition of GFP-fused mouse ANO1 channel expressed in HEK293A cells assessed as channel current amplitude at 10 uM at membrane potential of +80 mV measured after drug wash-out by patch clamp electrophysiology assay
Inhibition of GFP-fused mouse ANO1 channel expressed in HEK293A cells assessed as inhibition of current amplitude at 10 uM at membrane potential of +80 mV by patch clamp electrophysiology assay
Induction of ANO1 degradation in human U251 cells at 10 uM incubated for 24 hrs by western blot analysis
Assay data:2 Active, 2 Tested
Induction of ANO1 degradation in human U251 cells at 10 uM preincubated with compound for 6 hrs followed by treatment with proteasome inhibitor, MG132 for 18 hrs by western blot analysis
Inhibition of GFP-fused mouse ANO1 channel expressed in HEK293A cells assessed as inhibition of ATP-induced channel current amplitude at membrane potential of +80 mV by patch clamp electrophysiology assay
Assay data:11 Active, 2 Activity ≤ 1 µM, 11 Tested
Inhibition of human ANO1 channel expressed in HEK293 cells incubated for 10 mins by FLIPR assay
Assay data:10 Active, 1 Activity ≤ 1 µM, 10 Tested
Inhibition of human ANO1 channel expressed in HEK293 cells at 10 uM incubated for 10 mins by FLIPR assay relative to control
Assay data:36 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on