Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 18456241.

Inhibition of TRPV6 channel (unknown origin) by Patch-clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1845624

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18455972.

Inhibition of TRPV5 channel (unknown origin) by Patch-clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 5

Assay data:1 Active, 1 Tested

AID:: 1845597

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 16855413.

Inhibition of human TRPV5 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 5

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1685541

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16855404.

Inhibition of human TRPV6 expressed in human HEK293 cells assessed as reduction in Cd2+ influx at 10 uM by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Tested

AID:: 1685540

Summary PubMed Citation Related BioAssays by Target

Select item 16855385.

Inhibition of human TRPV6 expressed in human HEK293 cells assessed as reduction in Cd2+ influx at 50 uM by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:6 Tested

AID:: 1685538

Summary PubMed Citation Related BioAssays by Target

Select item 16855236.

Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in cadmium induced cytotoxicity by measuring increase in cell survival at 10 uM incubated for 24 hrs by XTT assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1685523

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 16855217.

Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx at 10 uM preincubated with compound followed by Cdcl2 addition measured for 12 to 30 mins by Leadmium-green and Alexafluor-594 conjugate based confocal microscopic analysis

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1685521

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 16855208.

Inhibition of human peYFP-C1 TRPV6 expressed in HEK293 cells assessed as decrease in whole cell calcium current at 10 uM at 50 mV holding potential in presence of La3+ by patch clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 2 Tested

AID:: 1685520

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 16855199.

Inhibition of human peYFP-C1 TRPV6 expressed in HEK293 cells assessed as decrease in whole cell calcium current at 0.1 uM at 50 mV holding potential in presence of La3+ by patch clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 2 Tested

AID:: 1685519

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 168551810.

Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx up to 100 uM by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Tested

AID:: 1685518

Summary PubMed Citation Related BioAssays by Target

Select item 168551711.

Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:16 Active, 12 Activity ≤ 1 µM, 16 Tested

AID:: 1685517

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 161168312.

Inhibition of TRPV5 channel (unknown origin)

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 5

Assay data:1 Tested

AID:: 1611683

Summary PubMed Citation Related BioAssays by Target

Select item 159017713.

Antagonist activity at human TRPV6 expressed in human HEK293 cells assessed as reduction in Ca2+ transport at 2.5 uM incubated for 5 mins by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1590177

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 159017514.

Agonist activity at human TRPV6 expressed in human HEK293 cells assessed as increase in Ca2+ transport at 100 nM incubated for 5 mins by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Tested

AID:: 1590175

Summary PubMed Citation Related BioAssays by Target

Select item 159017415.

Agonist activity at human TRPV6 expressed in human HEK293 cells assessed as increase in Ca2+ transport at 50 uM incubated for 5 mins by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Tested

AID:: 1590174

Summary PubMed Citation Related BioAssays by Target

Select item 151198816.

Inhibition of human YFP-fused TRPV6 expressed in HEK293 cells assessed as decrease in whole cell inward calcium current density at 10 uM at 50 mV holding potential pre-irradiated with 365 nm UV-light followed by 470 nm UV-light irradiation by patch clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1511988

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 151198717.

Inhibition of human YFP-fused TRPV6 expressed in HEK293 cells assessed as decrease in whole cell inward calcium current density at 10 uM at 50 mV holding potential under 365 nm UV-light irradiation by patch clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1511987

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 151198518.

Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1511985

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 151198019.

Inhibition of human peTFP-C1-TRPV6 expressed in HEK293 cells assessed as decrease in whole cell inward calcium current density at 10 uM at 50 mV holding potential by patch clamp assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:1 Active, 1 Tested

AID:: 1511980

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 151197920.

Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx preincubated for 5 mins followed by CdCl2 addition using 365 nm UV-light irradiated compound by calcium-5 fluorescence dye-based FLIPR assay

Source:: ChEMBL

Protein Target:: Transient receptor potential cation channel subfamily V member 6

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1511979

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioAssays with protein sequences specified as targets

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Active Compounds (21)
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Activity (IC50, etc) ≤ 1 µM (6)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (33)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1590174)
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PubChem BioAssay
Lysinibacillus sp. enrichment culture clone CB2-5 8b1 16S ribosomal RNA gene, pa...
Lysinibacillus sp. enrichment culture clone CB2-5 8b1 16S ribosomal RNA gene, partial sequence
gi|429537877|gb|JX992646.1|

Nucleotide
Same Parent, Connectivity for PubChem Compound (Select 51035062) (2)
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