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Inhibition of TRAF6 (unknown origin)-mediated NFkappaB activation expressed in human HeLaS3 cells harboring 3kappaB-tk-luc at 10 uM preincubated for 1 hr followed by Il1alpha-stimulation and measured after 3 hrs in presence of DTT by dual-luciferase reporter gene assay relative to control
Assay data:10 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of TRAF6 (unknown origin)-mediated NFkappaB activation expressed in human HeLaS3 cells harboring 3kappaB-tk-luc at 10 uM preincubated for 1 hr followed by Il1alpha-stimulation and measured after 3 hrs by dual-luciferase reporter gene assay relative to control
Assay data:2 Tested
Competitive inhibition of human TRAF6 interaction with biotinylated RANK peptide at 200 uM by NMR interaction analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human TRAF6 interaction with biotinylated RANK peptide by NMR interaction analysis
Assay data:4 Tested
Induction of human TRAF6 aggregation using biotinylated RANK peptide by NMR titration
Binding affinity to human TRAF6 using immobilized biotinylated RANK peptide from by SPR analysis
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