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KAT-7 Enzyme Assay from US Patent US11685732: "MYST family histone acetyltransferase inhibitors"
Assay data:336 Active, 407 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Kat7 Assay from US Patent US11492346: "Benzisoxazole sulfonamide derivatives"
Assay data:116 Active, 89 Activity ≤ 1 µM, 120 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of MYST2 (unknown origin) using Histone H3 substrate at 1 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MYST2 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of KAT7 (unknown origin)
Inhibition of MYST2 (unknown origin)
Assay data:2 Tested
Acetyltransferase Biochemical Assay from US Patent US11911372: "Compounds"
Assay data:78 Active, 42 Activity ≤ 1 µM, 126 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of KAT7 (unknown origin) assessed as reduction in H3K9ac acetylation at 10 uM relative to control
Inhibition of KAT7 (unknown origin) assessed as reduction in H3K14ac acetylation at 10 uM relative to control
Inhibition of HBO1 (unknown origin) using N-terminal histone H3 substrate at 100 uM by fluorescence assay in presence of [3H]acetyl-CoA relative to control
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