Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19630671.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1963067

Summary Related BioAssays by Target

Select item 19630662.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1963066

Summary Compounds, Active Related BioAssays by Target

Select item 19625443.

Nicotinic Acetylcholine Eurofins Panlabs panel

Source:: ChEMBL

Protein Targets:: Acetylcholine receptor subunit alpha; ...
Total:: 16

Assay data:1 Tested

AID:: 1962544

Summary Related BioAssays by Target

Select item 19623954.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962395

Summary Related BioAssays by Target

Select item 19623465.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962346

Summary Related BioAssays by Target

Select item 19622486.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962248

Summary Related BioAssays by Target

Select item 19622017.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962201

Summary Related BioAssays by Target

Select item 19621468.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962146

Summary Related BioAssays by Target

Select item 19621059.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962105

Summary Related BioAssays by Target

Select item 196206110.

N_NEURO_A4B2 Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1962061

Summary Related BioAssays by Target

Select item 196172711.

Binding affinity towards human CHRNA4 in an in vitro assay with cellular components measured by scintillation proximity assay

Source:: ChEMBL

Protein Target:: Neuronal acetylcholine receptor subunit alpha-4

Assay data:16 Active, 3 Activity ≤ 1 µM, 1170 Tested

AID:: 1961727

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193505712.

Binding affinity to alpha3beta4 nAChR (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-3; ...
Total:: 2

Assay data:12 Active, 9 Activity ≤ 1 µM, 12 Tested

AID:: 1935057

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193505613.

Binding affinity to alpha4beta2 nAChR (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:12 Active, 11 Activity ≤ 1 µM, 12 Tested

AID:: 1935056

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193505514.

Binding affinity to alpha7 nAChR (unknown origin) assessed as dissociation constant

Source:: ChEMBL

Protein Target:: Neuronal acetylcholine receptor subunit alpha-7

Assay data:12 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 12 Tested

AID:: 1935055

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 192577715.

Inhibition of alpha7 nAChR (unknown origin) at 10 uM

Source:: ChEMBL

Protein Target:: Neuronal acetylcholine receptor subunit alpha-7

Assay data:1 Tested

AID:: 1925777

Summary PubMed Citation Related BioAssays by Target

Select item 192577616.

Inhibition of alpha4beta4 nAChR (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1925776

Summary PubMed Citation Related BioAssays by Target

Select item 192577517.

Inhibition of alpha4beta2 nAChR (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-4; ...
Total:: 2

Assay data:1 Tested

AID:: 1925775

Summary PubMed Citation Related BioAssays by Target

Select item 192577418.

Inhibition of alpha3beta4 nAChR (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-3; ...
Total:: 2

Assay data:1 Tested

AID:: 1925774

Summary PubMed Citation Related BioAssays by Target

Select item 192302719.

Inhibition of human alpha3beta4 nAChR

Source:: ChEMBL

Protein Target:: Neuronal acetylcholine receptor subunit alpha-3

Assay data:2 Active, 2 Tested

AID:: 1923027

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 191948220.

Binding to Nicotinic Receptor Subtypes from US Patent US11667638: "4-substitued cytisine analogues"

Source:: BindingDB

Protein Targets:: Neuronal acetylcholine receptor subunit alpha-3; ...
Total:: 6

Assay data:50 Active, 3 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 50 Tested

AID:: 1919482

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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Target

Proteins (39)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,624)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (357)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,240)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (1,719)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (5)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (24)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (2,838)
BioAssays extracted from the literature
NIH MLP (27)
BioAssays deposited by the NIH Molecular Libraries Program
Other (35)
BioAssays deposited by other experimentalists

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