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Inhibition of ABCC6 (unknown origin) expressed in HEK293 cells assessed as increase in doxorubicin efflux at 100 uM after 30 mins by fluorescence assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: inhibition of photolabeling by IAARh123 (IAARh123: 1 uM, DOX: 1000 uM) in membranes from Mrp6-expressing P. pastoris
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: inhibition of photolabeling by IAARh123 (IAARh123: 1 uM, K571: 1000 uM) in membranes from Mrp6-expressing P. pastoris
TP_TRANSPORTER: inhibition of photolabeling by IAARh123 (IAARh123: 1 uM, LTC4: 300 uM) in membranes from Mrp6-expressing P. pastoris
TP_TRANSPORTER: inhibition of photolabeling by IAARh123 (IAARh123: 1 uM, VBL: 1000 uM) in membranes from Mrp6-expressing P. pastoris
TP_TRANSPORTER: inhibition of photolabeling by IAARh123 (IAARh123: 1 uM, VP-16: 1000 uM) in membranes from Mrp6-expressing P. pastoris
TP_TRANSPORTER: uptake in membrane vesicle from Mrp6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS in the presence of Benzbromarone at a concentration of 30uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS in the presence of Indomethacin at a concentration of 100uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS in the presence of Probenecid at a concentration of 1mM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: Northern blot in vivo SD rat, liver
Assay data:2 Tested
TP_TRANSPORTER: uptake in membrane vesicles from MRP6-expressing Sf9 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: uptake in membrane vesicle from MRP6-expressing CHO cells
Assay data:3 Tested
TP_TRANSPORTER: inhibition of NEM-GS by Benzbromarone at a concentration of 30uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS by Indomethacin at a concentration of 100uM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: inhibition of NEM-GS by Probenecid at a concentration of 1mM in membrane vesicles from MRP6-expressing Sf9 cells
TP_TRANSPORTER: drug resistance in MRP6-expressing CHO cells
Assay data:6 Tested
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