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HCV NS5B Pol assay ([32P]-UTP) from US Patent US11857560: "Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections"
Assay data:9 Active, 3 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
HCV NS5B Pol assay ([32P]-CTP]) from US Patent US11857560: "Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections"
Assay data:7 Active, 1 Activity ≤ 1 µM, 11 Tested
Inhibition of HCV genotype 6a NS5A
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of HCV genotype 5a NS5A
Inhibition of HCV genotype 4a NS5A
Inhibition of HCV genotype 3a NS5A
Inhibition of HCV genotype 2a NS5A
Inhibition of HCV genotype 1b NS5A
Inhibition of HCV genotype 1a NS5A
Rhinovirus Polymerase (HRV1bpol) and HCV Polymerase (HCVpol) Assays from US Patent US11149049: "Substituted nucleosides, nucleotides and analogs thereof"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Measuring Compound Inhibitory Potency from US Patent US11053243: "Inhibitors of hepatitis C virus replication"
Assay data:50 Active, 39 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 50 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition Assay from US Patent US10793591: "Substituted nucleosides, nucleotides and analogs thereof"
Assay data:15 Active, 14 Activity ≤ 1 µM, 15 Tested
HCV Polymerase Enzyme Assay from US Patent US10513534: "2′-chloro nucleoside analogs for HCV infection"
Assay data:10 Active, 2 Activity ≤ 1 µM, 11 Tested
Inhibition Assay from US Patent US9457039: "2′-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases"
Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested
Cell-Based HCV Replicon Assay from US Patent US9457039: "2′-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases"
Assay data:1 Active, 15 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
NS5B RNA Polymerase Assay from US Patent US9447132: "Highly active nucleoside derivative for the treatment of HCV"
Assay data:2 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Transient Transfection Assay from US Patent US9433609: "Benzimidazole-imidazole derivatives"
Assay data:20 Active, 18 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested
Stable Transfection Assay from US Patent US9433609: "Benzimidazole-imidazole derivatives"
Immumoenzymatic Assay from US Patent US9428491: "Substituted azoles, antiviral active component, pharmaceutical composition, method for preparation and use thereof"
Assay data:10 Active, 10 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Reporter Assay from US Patent US9428469: "Antiviral compounds"
Assay data:17 Active, 6 Activity ≤ 1 µM, 29 Tested
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