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Inhibition of human USP10 using ubiquitin rhodamine 110 as substrate at 10 to 50 uM by fluorometric assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Usp10 in mouse C2C12 cells assessed as reduction in phospho-sites occupancy at 4 uM after 5 hrs by SILAC based LC-MS/MS analysis relative to control
Assay data:1 Tested
USP10 deubiquitinase inhibition: Dose-response Confirmation
Assay data:529 Active, 1075 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
USP10 deubiquitinase inhibition: Primary qHTS
Assay data:509 Active, 47480 Tested
Binding affinity to USP10 in human A549 cells lysates grown on SILAC media at 10 uM incubated for 1 hr by LC-MS/MS analysis relative to untreated control
Binding affinity to ubiquitin carboxyl-terminal hydrolase 10 isoform-2 in human A549 cells at 0.15 mM after 4 hrs by HPLC-MS based pull down assay relative to control
Inhibition of USP10 (unknown origin) by Ub-AMC assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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