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Inhibition of Shigella dysenteriae Alexa-488 labelled STXB retrograde transport from endosome to trans golgi network in human HeLa cells at 1 uM incubated with cells for 1 hr prior to STXB challenge incubated for 30 mins in ice followed by 45 mins incubation at 37 degC by phalloidin-Atto-550/DAPI staining based confocal microscopic analysis
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
A qHTS for Small Molecule Inhibitors of Shiga Toxin (Summary)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
A qHTS for Small Molecule Inhibitors of Shiga Toxin (Confirmatory)
Assay data:100 Active, 14 Activity ≤ 1 nM, 125 Activity ≤ 1 µM, 506 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin (Confirmatory)
Assay data:17 Active, 6 Activity ≤ 1 µM, 506 Tested
A qHTS for Small Molecule Inhibitors of Shiga Toxin
Assay data:26913 Active, 293642 Tested
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin
Assay data:37055 Active, 296456 Tested
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