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Selectivity interaction (KinomeScan (DiscoverX)) EUB0000337aCl SNRK
Assay data:1 Tested
SummaryRelated BioAssays by Target
SNRK DiscoveRx kinase panel
SNRK(h) Kinase panel
Inhibition of SNRK (unknown origin) at 1 uM
SummaryPubMed CitationRelated BioAssays by Target
KinomeScan assay: inhibition of SNRK
Assay data:108 Tested
SNRK(h) Eurofins kinase panel
SNRK(h) Eurofins Kinase panel
SNRK(h) Millipore kinase panel
Inhibition of human SNRK assessed as percent of control at 2000 nM by KINOMEscan assay relative to control
Inhibition of DNA-tagged human SNRK assessed as percent of control at 50000 nM by qPCR analysis relative to control
Inhibition of human SNRK assessed as percent of control at 1000 nM by KINOMEscan assay relative to control
Inhibition of SNRK in human NCI-H929 cells at 10 uM by mass spectroscopic analysis relative to control
Assay data:6 Tested
Inhibition of SNRK in human NCI-H929 cells by mass spectroscopic analysis
Assay data:1 Active, 6 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of human SNRK (65 to 409 residues) assessed as residual activity at 10 uM using KKLRRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control
Inhibition of human SNRK assessed as residual activity using MBP as substrate at 1 uM by [gamma-33P]-ATP assay relative to control
Inhibition of human SNRK using MBP as substrate by [gamma-33P]-ATP assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to recombinant human SNRK E97G/P116A mutant (1 to 505 residues) using KKLRRTLSFAEPG peptide as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scintillation analysis
Inhibition of recombinant human SNRK E97G/P116A mutant (1 to 505 residues) using KKLRRTLSFAEPG peptide as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scintillation analysis
Assay data:5 Tested
Inhibition of human SNRK using MBP as substrate assessed as residual activity at 1 uM by [gamma-33P]-ATP assay relative to control
Assay data:2 Tested
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