Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Nicotinic Acetylcholine Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and measured for 1 to 5 days in presence of Ach stimulation by voltage-clamp based electrophysiological method
Assay data:12 Active, 7 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence of Ach stimulation by voltage-clamp based electrophysiological method
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential at 100 nM by two-electrode voltage clamp method
Assay data:5 Active, 26 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential by two-electrode voltage clamp method
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential at 10 uM by two-electrode voltage clamp method
Assay data:2 Active, 5 Tested
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holding potential at 1 uM by two-electrode voltage clamp method
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as rebound current at 100 uM treated for 1 sec at holding potential of -70 mVby two electrode voltage-clamp assay
Assay data:1 Active, 1 Tested
Partial agonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by measuring efficacy at 100 uM treated for 1 sec at holding potential of -70 mV by two electrode voltage-clamp assay relative to control
Assay data:4 Tested
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at 100 uM treated for 1 sec in presence of acetylcholine at holding potential of -70 mV by two electrode voltage-clamp assay relative to control
Assay data:2 Active, 13 Tested
Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response treated for 1 sec in presence of acetylcholine at holding potential of -70 mV by two electrode voltage-clamp assay
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Inhibition of rat nAChR alpha9alpha10 expressed in Xenopus laevis oocytes holding potential of -70 mV by two electrode voltage-clamp assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human nAChR alpha9alpha10 expressed in Xenopus laevis oocytes holding potential of -70 mV by voltage-clamp based electrophysiological method
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at 10 uM at -70 mV holding potential preincubated for 5 mins followed by Ach stimulation by voltage-clamp based electrophysiological method
Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential preincubated for 5 mins followed by Ach stimulation by voltage-clamp based electrophysiological method
Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method
Assay data:7 Active, 2 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
NACH/H Eurofins SafetyScreen44 (BI)
Antagonist activity at nAChR in human PC-3 cells assessed as reduction in cytoplasmic free calcium level at 5 uM measured upto 6 hrs by Fura2-AM dye based fluorescence assay
Antagonist activity at nAChR in human HT-29 cells assessed as reduction in cytoplasmic free calcium level at 5 uM measured upto 6 hrs by Fura2-AM dye based fluorescence assay
Antagonist activity at nAChR in human MDA-MB-231 cells assessed as reduction cytoplasmic free calcium level at 5 uM measured upto 6 hrs by Fura2-AM dye based fluorescence assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on