Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19638091.

hERG Qpatch Assay Protocol from US Patent US20240199576: "NOVEL CYCLOPENTA[C]PYRROL NEGATIVE ALLOSTERIC MODULATORS OF NR2B"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:3 Active, 5 Tested

AID:: 1963809

Summary Compounds, Active Related BioAssays by Target

Select item 19637862.

[3H]DA and [3H]5-HT Uptake Assay from US Patent US11999676: "Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 2

Assay data:90 Active, 90 Activity ≤ 1 µM, 91 Tested

AID:: 1963786

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19637063.

hERG Channel Inhibitory Activity Assay from US Patent US20240150370: "BICYCLIC PYRIDINE DERIVATIVE"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:2 Active, 39 Tested

AID:: 1963706

Summary Compounds, Active Related BioAssays by Target

Select item 19636124.

hERG Assay from US Patent US11970463: "Compounds and their use"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:1 Active, 35 Tested

AID:: 1963612

Summary Compounds, Active Related BioAssays by Target

Select item 19635395.

In Vitro Assay from US Patent US20240101531: "PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily KQT member 2; ...
Total:: 2

Assay data:373 Active, 166 Activity ≤ 1 µM, 419 Tested

AID:: 1963539

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19634656.

hERG Channel Activity from US Patent US11912693: "Compounds for modulating S1P1 activity and methods of using the same"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested

AID:: 1963465

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19634557.

Experimental Evaluation of the In Vitro Inhibitory Effect (IC50) of hERG from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"

Source:: BindingDB

Protein Targets:: Potassium voltage-gated channel subfamily H member 2; ...
Total:: 1

Assay data:15 Tested

AID:: 1963455

Summary Related BioAssays by Depositor Related BioAssays by Target

Select item 19632518.

Cross screening panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 5

Assay data:1 Tested

AID:: 1963251

Summary Related BioAssays by Target

Select item 19632509.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily E member 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1963250

Summary Related BioAssays by Target

Select item 196320310.

Cross screening panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 5

Assay data:1 Tested

AID:: 1963203

Summary Related BioAssays by Target

Select item 196320211.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily E member 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1963202

Summary Related BioAssays by Target

Select item 196315312.

Cross screening panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily A member 5

Assay data:1 Tested

AID:: 1963153

Summary Related BioAssays by Target

Select item 196315213.

Cross screening panel

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily E member 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1963152

Summary Related BioAssays by Target

Select item 196315114.

Cross screening panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1963151

Summary Related BioAssays by Target

Select item 196306515.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily E member 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1963065

Summary Related BioAssays by Target

Select item 196306416.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Targets:: Potassium voltage-gated channel subfamily KQT member 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1963064

Summary Related BioAssays by Target

Select item 196306117.

Safety47 Scan (DiscoverX - Eurofins)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1963061

Summary Related BioAssays by Target

Select item 196256918.

Potassium Channel hERG Eurofins Panlabs panel

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962569

Summary Related BioAssays by Target

Select item 196238419.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962384

Summary Related BioAssays by Target

Select item 196233520.

HERG_DOFETILIDE Eurofins SafetyScreen44 (BI)

Source:: ChEMBL

Protein Target:: Potassium voltage-gated channel subfamily H member 2

Assay data:1 Tested

AID:: 1962335

Summary Related BioAssays by Target

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Proteins (107)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,965)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (38)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (920)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (6)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (2,994)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (32)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (97)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (4,889)
BioAssays extracted from the literature
NIH MLP (99)
BioAssays deposited by the NIH Molecular Libraries Program
Other (134)
BioAssays deposited by other experimentalists

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PubChem BioAssay
Nucleotide Links for Gene (Select 367302) (7)
Nucleotide
carbamate kinase [Oenococcus oeni]
carbamate kinase [Oenococcus oeni]
gi|488909732|ref|WP_002820807.1|

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