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Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in presence of NADH by fluorescence assay
Assay data:37 Active, 29 Activity ≤ 1 µM, 39 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Cellular mechanistic assay ? BCAA measurement (U-87-MG cells)
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Biochemical assay (BCAT1)
Inhibition of BCATc (unknown origin)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human recombinant histidine-tagged BCATc expressed in Escherichia coli BL21 (DE3) after 50 mins using [13C]-L-leucine as substrate by NMR spectroscopy analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of rat BCATm
Assay data:1 Active, 1 Tested
Inhibition of rat BCATc
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human BCATc
Assay data:9 Active, 1 Activity ≤ 1 µM, 20 Tested
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