Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of ALK L1196M mutant (unknown origin) using biotin-TK peptide as substrate in presence of ATP incubated for 90 mins by HTRF assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of ALK C1156Y mutant (unknown origin) using biotin-TK peptide as substrate in presence of ATP incubated for 90 mins by HTRF assay
Inhibition of wild type ALK (unknown origin) using biotin-TK peptide as substrate in presence of ATP incubated for 90 mins by HTRF assay
Inhibition of ALK (unknown origin) at 1000 nM by by DiscoverX KINOMEscan assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human ALK at 200 nM by Z'-lyte assay
Inhibition of ALK (unknown origin) at 1 uM relative to control
Inhibition of ALK G1202R mutant (unknown origin)
Assay data:20 Active, 20 Activity ≤ 1 µM, 20 Tested
Inhibition of wild type ALK (unknown origin)
Inhibition of ALK (unknown origin) pre-incubated for 10 mins followed by substrate addition measured after 60 mins in presence of ATP by mobility shifting assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of ALK L1196M mutant (unknown origin)
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of ALK (unknown origin)
Binding affinity to human recombinant ALK L1196M mutant (1093 to 1411 residues) assessed as inhibition constant using 5'FAM-KKSRGDYMTMQIG-CONH2 peptide as substrate in presence of ATP by micro-fluidic mobility shift assay
Inhibition of human partial length ALK (I1088/E1409) expressed in mammalian system at 1 uM by KINOMEscan analysis relative to control
Inhibition of N-terminal GST-tagged human ALK cytoplasmic domain (1058 to 1620 residues) L1196M mutant expressed in baculovirus-infected Sf21 cells using LANCE Ultra ULight-PolyGT substrate incubated for 2 hrs by TR-FRET assay
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
Inhibition of N-terminal GST-tagged human ALK cytoplasmic domain (1058 to 1620 residues) C1156Y mutant expressed in baculovirus-infected Sf21 cells using LANCE Ultra ULight-PolyGT substrate incubated for 2 hrs by TR-FRET assay
Inhibition of N-terminal GST-tagged human wild type ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus-infected Sf21 cells using LANCE Ultra ULight-PolyGT substrate incubated for 2 hrs by TR-FRET assay
Inhibition of N-terminal GST-tagged human wild type ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus-infected Sf21 cells using LANCE Ultra ULight-PolyGT substrate at 100 nM incubated for 2 hrs by TR-FRET assay
Assay data:8 Tested
Inhibition of ALK (unknown origin) by radiometric ATP-competitive kinase assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on