Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19636091.

Enzymatic Inhibitory Activity (IC50) Assay from US Patent US20240132517: "MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF"

Source:: BindingDB

Protein Targets:: Hepatocyte growth factor receptor; ...
Total:: 3

Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1963609

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19629592.

SRC SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1962959

Summary Related BioAssays by Target

Select item 19628553.

SRC SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1962855

Summary Related BioAssays by Target

Select item 19627594.

SRC SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1962759

Summary Related BioAssays by Target

Select item 19626605.

SRC SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1962660

Summary Related BioAssays by Target

Select item 19624506.

SRC Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1962450

Summary Related BioAssays by Target

Select item 19624197.

LYN A Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lyn

Assay data:1 Tested

AID:: 1962419

Summary Related BioAssays by Target

Select item 19623038.

SRC Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1962303

Summary Related BioAssays by Target

Select item 19622729.

LYN A Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lyn

Assay data:1 Tested

AID:: 1962272

Summary Related BioAssays by Target

Select item 196086710.

Inhibition of LYN (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lyn

Assay data:1 Tested

AID:: 1960867

Summary PubMed Citation Related BioAssays by Target

Select item 196086611.

Inhibition of c-Src (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1960866

Summary PubMed Citation Related BioAssays by Target

Select item 195838812.

Inhibition of Yes (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Yes

Assay data:3 Tested

AID:: 1958388

Summary PubMed Citation Related BioAssays by Target

Select item 195838513.

Inhibition of Src (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:3 Tested

AID:: 1958385

Summary PubMed Citation Related BioAssays by Target

Select item 195646514.

Inhibition of His-tagged human recombinant BLK expressed in insect cells at 200 nM by Z'-lyte assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1956465

Summary PubMed Citation Related BioAssays by Target

Select item 195645115.

Inhibition of His-tagged human recombinant FYN expressed in insect cells at 200 nM by Z'-lyte assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Fyn

Assay data:1 Tested

AID:: 1956451

Summary PubMed Citation Related BioAssays by Target

Select item 195644816.

Inhibition of human LYN at 200 nM by Z'-lyte assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Lyn

Assay data:1 Tested

AID:: 1956448

Summary PubMed Citation Related BioAssays by Target

Select item 195593117.

Inhibition of YES (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Yes

Assay data:1 Tested

AID:: 1955931

Summary PubMed Citation Related BioAssays by Target

Select item 195591318.

Inhibition of SRC (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Tested

AID:: 1955913

Summary PubMed Citation Related BioAssays by Target

Select item 195591219.

Inhibition of FGR (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Fgr

Assay data:1 Tested

AID:: 1955912

Summary PubMed Citation Related BioAssays by Target

Select item 195448320.

Inhibition of SRC (unknown origin) by Z'LYTE assay

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1954483

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (15)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,313)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (175)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (1,054)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (1,589)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Assay Project (5)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (3,499)
BioAssays extracted from the literature
NIH MLP (5)
BioAssays deposited by the NIH Molecular Libraries Program
Other (241)
BioAssays deposited by other experimentalists

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