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Summary
TBD from US Patent US11530198: "Compositions and methods for treating infections"
Assay data:58 Active, 25 Activity ≤ 1 µM, 63 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of DHFR (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of DHFR (unknown origin) assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of DHFR (unknown origin) at pH 6.7
Inhibition of recombinant human DHFR expressed in Escherichia coli BL21 (DE3) cells using dihydrofolate as substrate in presence of NADPH by spectrophotometric analysis
Assay data:6 Active, 1 Activity ≤ 1 µM, 34 Tested
Inhibition of recombinant human DHFR expressed in Escherichia coli incubated for 15 mins and measured by ELISA
Assay data:7 Active, 5 Activity ≤ 1 µM, 7 Tested
Kinase Inhibition Assay from US Patent US11111252: "Pyrimidine compounds and pyrimido indole compounds and methods of use"
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
Inhibitory Activity Assay from US Patent US11078214: "Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same"
Assay data:17 Active, 17 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
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