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assay on hold
Summary
Surface Plasmon Resonance Assay from US Patent US20240197735: "METHODS AND COMPOSITIONS COMPRISING A BRAF INHIBITOR AND A PD-1 BINDING ANTAGONIST"
Assay data:4 Active, 2 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Measurement of FXIa Inhibition from US Patent US20240174633: "CRYSTALLINE FORMS OF (4S)-24-CHLORO-4-ETHYL-73-FLUORO-35-METHOXY-32,5-DIOXO-14-(TRIFLUORO-METHYL)-32H-6-AZA-3(4,1)-PYRIDINA-1(1)-[1,2,3]TRIAZOLA-2(1,2),7(1)-DIBENZENAHEPTAPHANE-74-CARBOXAMIDE"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Kinase Assay from US Patent US20240174621: "METHYLQUINAZOLINONE DERIVATIVES"
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
ADP-Glo Kinase Assay from US Patent US20240158408: "Nitrogen-Containing Heterocyclic Compound, Pharmaceutical Compositions thereof and Use thereof"
Assay data:78 Active, 13 Activity ≤ 1 µM, 162 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
PI3Kα and PI3KαH1047R Enzyme Activity Inhibition Evaluation Assay from US Patent US20240158408: "Nitrogen-Containing Heterocyclic Compound, Pharmaceutical Compositions thereof and Use thereof"
Assay data:149 Active, 103 Activity ≤ 1 µM, 162 Tested
HCK Kinase Assay from US Patent US11963960: "Compounds for treating or inhibiting recurrence of acute myeloid leukemia"
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
Enzymatic Inhibitory Activity (IC50) Assay from US Patent US20240132517: "MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF"
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
VEGFR ADP GLO Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:23 Active, 13 Activity ≤ 1 µM, 485 Tested
PDGFRβ LanthaScreen Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:478 Active, 11 Activity ≤ 1 nM, 468 Activity ≤ 1 µM, 485 Tested
PDGFRβ HTRF Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:485 Active, 377 Activity ≤ 1 nM, 483 Activity ≤ 1 µM, 485 Tested
ABL1 Biochemical Kinase Assay from US Patent US20240101536: "COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS"
Assay data:217 Active, 190 Activity ≤ 1 nM, 217 Activity ≤ 1 µM, 217 Tested
In Vitro Enzymatic Activity Assay from US Patent US20240083917: "Polycyclic Kinase Inhibitor"
Assay data:19 Active, 5 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
PI3K-delta Scintillation Proximity Assay from US Patent US11926616: "Aminopyrazine diol compounds as PI3K-γ inhibitors"
Assay data:46 Active, 43 Activity ≤ 1 µM, 46 Tested
Mobility-Shift Assay from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"
Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested
In Vitro Kinase Binding Assay from US Patent US20240058459: "DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO THE EYE"
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Cross screening panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
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