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Inhibition of 6PGD in human A38-5 cells assessed as increase in Ru-5-P level at 15.6 uM incubated for 72 hrs by mass spectrometry
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of 6PGD in human A38-5 cells assessed as fold increase in 6PG level at 15.6 uM incubated for 72 hrs by mass spectrometry
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of 6PGD in human A38-5 cells assessed as increase in Ru-5-P level at 250 uM incubated for 72 hrs by mass spectrometry
Inhibition of 6PGD in human A38-5 cells assessed as fold increase in 6PG level at 250 uM incubated for 72 hrs by mass spectrometry
Inhibition of 6PGD in human A38-5 cells assessed as increase in intracellular H3K9me3 expression level at 1 to 250 uM incubated for 72 hrs by western blot analysis
Inhibition of 6PGD in human A38-5 cells assessed as fold increase in intracellular H3K9me3 level at 15.6 uM incubated for 45 mins by HTRF assay
Inhibition of 6PGD in human A38-5 cells assessed as increase in intracellular H3K9me3 level at 1 uM incubated for 45 mins by HTRF assay
Inhibition of 6PGD in human A38-5 cells assessed as increase in intracellular H3K9me3 level upto 250 uM incubated for 45 mins by HTRF assay
Inhibition of 6PGD in human A38-5 cells assessed as fold increase in intracellular H3K9me3 level at 250 uM incubated for 45 mins by HTRF assay
Inhibition of 6PGD in human A38-5 cells assessed as increase in intracellular H3K9me3 level at 0.1 to 1000 uM incubated for 45 mins by HTRF assay
Assay data:3 Active, 10 Tested
In Vitro Assay from Article 10.3109/14756360903257900: "Effects of some drugs on human erythrocyte 6-phosphogluconate dehydrogenase: an in vitro study."
Assay data:1 Active, 7 Tested
Enzyme Assay from Article 10.1080/14756360701546413: "Investigation of the effects of some sulfonamide derivatives on the activities of glucose-6-phosphate dehydrogenase, 6-phospho gluconate dehydrogenase and glutathione reductase from human erythrocytes."
Assay data:2 Active, 5 Tested
Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening
Assay data:15 Active, 2000 Tested
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of sheep 6-phosphogluconate dehydrogenase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of sheep 6PGDH
Inhibition of sheep 6PGDH expressed in Escherichia coli by spectroscopy
Assay data:3 Active, 1 Activity ≤ 1 µM, 6 Tested
Inhibition of 6PGD
Assay data:4 Active, 2 Activity ≤ 1 µM, 8 Tested
log Kd which is the binding affinity against 6-phosphogluconate dehydrogenase
Inhibition constant against 6-phosphogluconate dehydrogenase of sheep liver; NI denotes no inhibition
Assay data:4 Tested
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