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MGAT LCMS Assay from US Patent US11479538: "Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors"
Assay data:24 Active, 24 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition Assay from US Patent US9035059: "Nitrogen-containing condensed heterocyclic compound"
Assay data:48 Active, 48 Activity ≤ 1 µM, 48 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Assay data:96 Active, 96 Activity ≤ 1 µM, 96 Tested
Inhibition Assay from US Patent US8993568: "Morpholinyl derivatives useful as MOGAT-2 inhibitors"
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of mouse recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluorescence assay
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human recombinant MGAT2 assessed as reduction in enzyme-mediated deacylation of oleoyl-CoA incubated for 20 mins by CPM dye based fluorescence assay
Assay data:17 Active, 7 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human MoGAT-2 expressed in human Caco2 cells assessed as inhibition of 2-O-Hexadecylglycerol hydrolysis pretreated for 30 mins by LC-MS analysis
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of human MGAT2 by Rapidfire LCMS assay
Assay data:19 Active, 16 Activity ≤ 1 µM, 25 Tested
Inhibition of human MGAT2 by SPA assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested
Inhibition of human MGAT2 by LC/MS assay
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