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Summary
Thermal Shift Assay. Domain: start/stop: R65-L423
Assay data:26 Tested
SummaryRelated BioAssays by Target
Competition Binding Assays from Article 10.1021/acschembio.5b01063: "Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors."
Assay data:26 Active, 2 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Assay data:34 Active, 2 Activity ≤ 1 µM, 243 Tested
In vitro activity on S. mansoni schistosomula at 50 uM
Assay data:1 Active, 400 Tested
SummaryCompounds, Active
Stabilization of FECH in human K562 cells after 1 hr by thermal shift assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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