Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Selectivity interaction (MDS Pharma Service panel (GPCR, ion channels, receptors, and other enzymes, radioligand binding assays)) EUB0000294b NISCH
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (Enzyme panel (receptors, ion channels, other enzymes)) EUB0000679a NISCH
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
I1 Receptor Binding Assay from US Patent US9303019: "Amino-pyrroline derivatives, and use thereof in the prevention and/or treatment of metabolic syndrome"
Assay data:6 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Displacement of [3H]clonidine from I1IR in human brain frontal cortex in presence of adrenaline incubated for 45 mins by liquid scintillation spectrometry
Assay data:13 Active, 7 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [125I]-p-iodoclonidine from I1 receptor imidazoline binding site in rat PC12 cell membranes after 30 mins by gamma counting method
Displacement of [125I]-p-iodoclonidine from I1 receptor imidazoline binding site in Sprague-Dawley rat kidney cell membranes after 30 mins by liquid scintillation counting
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Displacement of [125I]PIC from Imidazoline-1 receptor in rat PC12 cell membrane by gamma counting method
Assay data:10 Active, 6 Activity ≤ 1 µM, 10 Tested
Displacement of [125I]PIC from Imidazoline-1 receptor in rat PC12 cell membrane incubated for 30 mins by gamma counting method
Assay data:7 Active, 2 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 7 Tested
Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting
Assay data:7 Active, 4 Activity ≤ 1 µM, 14 Tested
Displacement of [125I]-p-iodoclonidin from I1-imidazoline receptor in rat PC12 cell membranes
Assay data:13 Active, 12 Activity ≤ 1 µM, 15 Tested
Displacement of [125I] PIC from I1 imidazoline receptor in rat PC12 cells after 45 mins by gamma counting
Assay data:19 Active, 3 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 27 Tested
Displacement of [3H]2BF1 from imidazoline I1 receptor in Sprague-Dawley rat kidney membranes after 45 mins by liquid scintillation counting
Assay data:5 Active, 1 Activity ≤ 1 µM, 9 Tested
Binding affinity to I1 imidazoline binding site in Rattus norvegicus (rat) PC12 cells
Assay data:25 Active, 3 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 25 Tested
Development of inhibitors for mGluR7 (Eurofin Panel Assay Results)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Development of inhibitors for Menin-MLL Receptor(Eurofin Panel Assay Results)
Development of inhibitors for mGluR7/8 (Eurofin Panel Assay Results)
Development of inhibitors for PLD2 (Eurofin Panel Assay Results)
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of inhibitors for Dopamine D4 Receptors: Eurofin Panel Assay Results
Development of the first CNS penetrant Muscarinic 5 (M5) Positive Allosteric Modulator based on a novel non-isatin core
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Development of a novel orthosteric Muscarinic 5 (M5) antagonist possessing a hig degree of muscarinic subtype selectivity
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on